Evidence map›Paper›PMID 34103361›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Comodulation of h- and Na

Parker J Ellingson, William H Barnett, Daniel Kueh, Alex Vargas, Ronald L Calabrese, Gennady S Cymbalyuk

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Circuit-constrained molecular neuroethology in the medicinal leech Hirudo verbana.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The sigh and related behaviors.Handbook of clinical neurology · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Parker J EllingsonNeuroscience Institute, Georgia State University, Atlanta, Georgia 30303.
William H BarnettNeuroscience Institute, Georgia State University, Atlanta, Georgia 30303.
Daniel KuehDepartment of Biology, Emory University, Atlanta, Georgia 30322.
Alex VargasNeuroscience Institute, Georgia State University, Atlanta, Georgia 30303.
Ronald L CalabreseDepartment of Biology, Emory University, Atlanta, Georgia 30322.ORCID https://orcid.org/0000-0001-7135-3469
Gennady S CymbalyukNeuroscience Institute, Georgia State University, Atlanta, Georgia 30303 gcymbalyuk@gsu.edu.
Georgia State University · USEmory University · US

Funding

An In Vivo Voltammetric Serotonin Biomarker for Antidepressant EfficacyR01MH106563 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HASHEMI, PARASTOO · 2016 to 2020
$1.6M
Role of Na+/K+ pump in rhythm generation of a motor control circuitR21NS111355 · NINDS · GEORGIA STATE UNIVERSITY · PI CALABRESE, RONALD L, CYMBALYUK, GENNADY S · 2019 to 2019
$439k
NIMH NIH HHS R01 MH106563NINDS NIH HHS R21 NS111355
6 · The paper itself

Abstract

Central pattern generators (CPGs), specialized oscillatory neuronal networks controlling rhythmic motor behaviors such as breathing and locomotion, must adjust their patterns of activity to a variable environment and changing behavioral goals. Neuromodulation adjusts these patterns by orchestrating changes in multiple ionic currents. In the medicinal leech, the endogenous neuromodulator myomodulin speeds up the heartbeat CPG by reducing the electrogenic Na

Indexed as

Models, NeurologicalAction PotentialsAnimalsCentral Pattern GeneratorsComputer SimulationInterneuronsLeechesNeuropeptidesSodium-Potassium-Exchanging ATPasemyomodulinNeuropeptidesSodium-Potassium-Exchanging ATPasehalf-center oscillatorinvertebrateleechneuromodulationoscillatory networksseizure-like oscillations

Identifiers

PMID34103361
PMCPMC8318076
OpenAlexW3167842783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.