Evidence map›Paper›PMID 34103172›Full record

ArticleJournal of manipulative and physiological therapeutics2021

Effects of Thrust Magnitude and Duration on Immediate Postspinal Manipulation Trunk Muscle Spindle Responses.

Carla R Lima, Randall S Sozio, AaMarryah C Law, Alicia J Nelson, Harshvardhan Singh, Christopher P Hurt, Peng Li, William R Reed

Open access · greenAbstract read
In one paragraph

Article in Journal of manipulative and physiological therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Carla R LimaRehabilitation Science Program, University of Alabama at Birmingham, Birmingham, Alabama.
Randall S SozioPalmer Center for Chiropractic Research, Palmer College of Chiropractic, Davenport, Iowa.
AaMarryah C LawCORD Program, University of Alabama at Birmingham, Birmingham, Alabama.
Alicia J NelsonCORD Program, University of Alabama at Birmingham, Birmingham, Alabama.
Harshvardhan SinghPhysical Therapy Department, University of Alabama at Birmingham, Birmingham, Alabama.
Christopher P HurtPhysical Therapy Department, University of Alabama at Birmingham, Birmingham, Alabama.
Peng LiSchool of Nursing, University of Alabama at Birmingham, Birmingham, Alabama.
William R ReedPalmer Center for Chiropractic Research, Palmer College of Chiropractic, Davenport, Iowa; Physical Therapy Department, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: wreed@uab.edu.
University of Alabama at Birmingham · USPalmer College of Chiropractic · US

Funding

Vertebral Displacements & Ligament Strains during Simul. Spinal Mani./Gudavalli,RU19AT004137 · NCCIH · PALMER COLLEGE OF CHIROPRACTIC · PI PICKAR, JOEL G · 2007 to 2010
$4.5M
RENOVATION OF PALMER CENTER FOR CHIROPRACTIC RESEARCHC06RR015433 · NCRR · PALMER COLLEGE OF CHIROPRACTIC · PI MEEKER, WILLIAM C · 2000 to 2000
$1.3M
Effect of Lumbar Hypo & Hypermobility on Sensory Responses to Spinal ManipulationK01AT005935 · NCCIH · PALMER COLLEGE OF CHIROPRACTIC · PI REED, WILLIAM RAY · 2010 to 2014
$638k
Proprioceptive mechanisms underlying post-spinal manipulation response in an NGF-induced low back pain modelR21AT010517 · NCCIH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI REED, WILLIAM RAY · 2019 to 2020
$407k
NCCIH NIH HHS K01 AT005935NCCIH NIH HHS R21 AT010517NCCIH NIH HHS U19 AT004137NCRR NIH HHS C06 RR015433
6 · The paper itself

Abstract

objectiveThe purpose of this study was to characterize trunk muscle spindle responses immediately after high-velocity, low-amplitude spinal manipulation (HVLA-SM) delivered at various thrust magnitudes and thrust durations.

methodsSecondary analysis from multiple studies involving anesthetized adult cats (N = 70; 2.3-6.0 kg) receiving L6 HVLA-SM. Muscle spindle afferent recordings were obtained from L6 dorsal rootlets before, during, and immediately after HVLA-SM. L6 HVLA-SM was delivered posteriorly-to-anteriorly using a feedback motor with peak thrust magnitudes of 25%, 55%, and 85% of cat body weight (BW) and thrust durations of 25, 50, 75, 100, 150, 200, and 250 ms. Time to the first action potential and muscle spindle discharge frequency at 1 and 2 seconds post-HVLA-SM were determined.

resultsA significant association between HVLA-SM thrust magnitude and immediate (≤2 s) muscle spindle response was found (P < .001). For non-control thrust magnitude, pairwise comparisons (25%, 55%, 85% BW), 55% BW thrust magnitude had the most consistent effect on immediate post-HVLA-SM discharge outcomes (false discovery rate < 0.05). No significant association was found between thrust duration and immediate post-HVLA-SM muscle spindle response (P > .05).

conclusionThe present study found that HVLA-SM thrust magnitudes delivered at 55% BW were more likely to affect immediate (≤2 s) post-HVLA-SM muscle spindle response.

Indexed as

Manipulation, SpinalMuscle SpindlesAnimalsCatsMuscle, SkeletalSpinal Nerve RootsTorsoBack MusclesManipulation, SpinalMuscle SpindlesMusculoskeletal ManipulationsNeurophysiology

Identifiers

PMID34103172
PMCPMC8453039
OpenAlexW3172105750

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.