Evidence map›Paper›PMID 34103035›Full record

Observational studyBMC surgery2021

Pattern of symptom improvement following endoscopic sinus surgery for chronic rhinosinusitis.

Salma S Al Sharhan, Mohammed H Al Bar, Shahad Y Assiri, Assayl R AlOtiabi, Deemah M Bin-Nooh, Fozia K AlSugair, Nada F AlRashidi, Abdulmalik S AlSaied, Amal A Alghamdi

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Salma S Al SharhanDepartment of Otorhinolaryngology, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia. Ssalsharhan@iau.edu.sa.ORCID http://orcid.org/0000-0002-7708-8368
Mohammed H Al BarDepartment of Otorhinolaryngology, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.
Shahad Y AssiriDepartment of Otorhinolaryngology, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.
Assayl R AlOtiabiDepartment of Otorhinolaryngology, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.
Deemah M Bin-NoohDepartment of Otorhinolaryngology, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.
Fozia K AlSugairDepartment of Otorhinolaryngology, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.
Nada F AlRashidiDepartment of Otorhinolaryngology, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.
Abdulmalik S AlSaiedDepartment of Otorhinolaryngology, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.
Amal A AlghamdiDivision of Epidemiology and Biostatistics, Department of Family and Community Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.
Imam Abdulrahman Bin Faisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic rhinosinusitis (CRS) is a common inflammation of the nose and the paranasal sinuses. Intractable CRS cases are generally treated with endoscopic sinus surgery (ESS). Although the effect of ESS on CRS symptoms has been studied, the pattern of symptom improvement after ESS for CRS is yet to be investigated. The aim of this study was to determine the magnitude and sequence of symptom improvement after ESS for CRS, and to assess the possible preoperative factors that predict surgical outcomes in CRS patients.

methodsThis was a longitudinal prospective study of 68 patients who had CRS (with or without nasal polyps). The patients underwent ESS at King Fahd Hospital of the University, Al Khobar, Saudi Arabia. The Sino-nasal Outcome Test-22 (SNOT-22) questionnaire was used for assessment at four time points during the study: pre-ESS, 1-week post-ESS, 4 weeks post-ESS, and 6 months post-ESS.

resultsThe difference between the mean scores recorded for the five SNOT-22 domains pre-ESS and 6 months post-ESS were as follows: rhinologic symptoms (t-test = 7.22, p-value =  < 0.001); extra-nasal rhinologic symptoms (t-test = 4.87, p-value =  < 0.001); ear/facial symptoms (t-test = 6.34, p-value =  < 0.001); psychological dysfunction (t-test = 1.99, p-value = 0.049); and sleep dysfunction (t-test = 5.58, p-value =  < 0.001). There was a significant difference between the mean scores recorded for the five domains pre-ESS and 6 months post-ESS. Rhinologic symptoms had the largest effect size (d = 1.12), whereas psychological dysfunction had the least effect size (d = 0.24). The only statistically significant difference in the SNOT-22 mean scores recorded 4 weeks post-ESS was observed between allergic and non-allergic patients (t = - 2.16, df = 66, p = 0.035).

conclusionUnderstanding the pattern of symptom improvement following ESS for CRS will facilitate patient counselling and aid the optimization of the current treatment protocols to maximize surgical outcomes and quality of life. LEVEL OF EVIDENCE: Prospective observational.

Indexed as

Nasal PolypsRhinitisSinusitisChronic DiseaseEndoscopyHumansProspective StudiesQuality of LifeTreatment OutcomeChronic rhinosinusitisNasal polypsPattern of symptomsQuality of life

Identifiers

PMID34103035
PMCPMC8188672
OpenAlexW3170609770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.