Evidence map›Paper›PMID 34103001›Full record

ArticleBMC medical imaging2021

Correlations between apparent diffusion coefficient values of WB-DWI and clinical parameters in multiple myeloma.

Bei Zhang, Bingyang Bian, Zhiwei Zhao, Fang Lin, Zining Zhu, Mingwu Lou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Bei ZhangShenzhen Clinical Medical School, Guangzhou University of Chinese Medicine, Shenzhen, China.
Bingyang BianDepartment of Radiology, First Hospital of Jilin University, Changchun, China.
Zhiwei ZhaoDepartment of Hand and Foot Surgery, First Hospital of Jilin University, Changchun, China.
Fang LinDepartment of Radiology, First Hospital of Jilin University, Changchun, China.
Zining ZhuDepartment of Radiology, First Hospital of Jilin University, Changchun, China.
Mingwu LouShenzhen Clinical Medical School, Guangzhou University of Chinese Medicine, Shenzhen, China. mingwulou@yeah.net.
First Hospital of Jilin University · CNJilin University · CNLonggang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhole-body diffusion-weighted imaging (WB-DWI) is a method for evaluating bone marrow infiltration in multiple myeloma (MM). This study seeks to elucidate the correlation between the apparent diffusion coefficient (ADC) value and some selected clinical parameters.

methodsA total of 101 Chinese patients with MM who had undergone WB-DWI from May 2017 to May 2019 were enrolled in this study. The ADC values of the MM lesions and the clinical parameters were quantified at the first (baseline) visit and after four-course induction chemotherapy. Multiple linear regression and logistic analyses were carried out to find the implicit inherent relationships within the patients' data.

resultsThe paired Wilcoxon test showed that the ADC values at the baseline visit (ADC

conclusionThe ADC values of WB-DWI may be associated with clinical parameters of MM including the fluorescence in situ hybridization result, and may be useful in the prognosis of patients with MM.

trial registrationChiCTR2000029587.

Indexed as

beta 2-MicroglobulinBone MarrowDiffusion Magnetic Resonance ImagingFemaleGene RearrangementGenes, Immunoglobulin Heavy ChainHumansImmunoglobulin lambda-ChainsInduction ChemotherapyIn Situ Hybridization, FluorescenceLinear ModelsMaleMiddle AgedMultiple MyelomaRetrospective StudiesStatistics, Nonparametricbeta 2-MicroglobulinImmunoglobulin lambda-ChainsApparent diffusion coefficientDiffusion-weighted imagingFISHMultiple myelomaTherapeutic response

Identifiers

PMID34103001
PMCPMC8186136
OpenAlexW3172619306

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.