Evidence map›Paper›PMID 34102981›Full record

ArticleCurrent medical imaging2021

Perilesional Lymph Node Swelling Might be a Radiologic Clue for Appendiceal Schwannoma: A Case Report.

Kunihito Suzuki, Kazuhiro Saito, Takafumi Yamada, Elly Arizono, Hidehiro Kumita, Kenta Kasahara, Kenji Katsumata, Koichiro Tasaki, Jun Matsubayashi, Toshitaka Nagao

Abstract readCase Reports
In one paragraph

Article in Current medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Schwannoma of the Appendix Mimicking a Metastatic Breast Cancer:Sultan Qaboos University medical journal · 2025
    Article
  2. Multiple Gastric Schwannoma: A Case Report.Current medical imaging · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kunihito SuzukiDepartment of Radiology, Tokyo Medical University, Tokyo, Japan.
Kazuhiro SaitoDepartment of Radiology, Tokyo Medical University, Tokyo, Japan.
Takafumi YamadaDepartment of Radiology, Tokyo Medical University, Tokyo, Japan.
Elly ArizonoDepartment of Radiology, Tokyo Medical University, Tokyo, Japan.
Hidehiro KumitaDepartment of Radiology, Tokyo Medical University, Tokyo, Japan.
Kenta KasaharaDepartment of Gastrointestinal and Pediatric Surgery, Tokyo Medical University, Tokyo, Japan.
Kenji KatsumataDepartment of Gastrointestinal and Pediatric Surgery, Tokyo Medical University, Tokyo, Japan.
Koichiro TasakiDepartment of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan.
Jun MatsubayashiDepartment of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan.
Toshitaka NagaoDepartment of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal schwannoma is not a common type of tumor, and lesions originating from the appendix are extremely rare. Herein, we report a patient with appendiceal schwannoma characterized by lymph node swelling. CASE REPORT: A 67-year-old male patient who had diabetes complained of weight loss. A computed tomography scan revealed a mass in the right side of the pelvic cavity. Moreover, a contrast-enhanced computed tomography scan showed perilesional lymph node swelling measuring up to 28 mm. A low-intensity mass was observed on T1-weighted imaging, heterogeneous high-intensity mass on T2-weighted imaging, and restricted diffusion on diffusion-weighted imaging. There were no abnormal findings on colonoscopy. Based on a preoperative examination, a differential diagnosis of either appendiceal schwannoma, carcinoid, or gastrointestinal stromal tumor was considered. During surgery, a large appendiceal mass and multiple swollen perilesional lymph nodes were observed. Therefore, ileocecal resection and D3 lymph node dissection were performed. Pathological and immunohistochemical analyses confirmed the diagnosis of appendiceal schwannoma. There were numerous swollen lymph nodes in the mesenteric region. The lymph nodes revealed reactive lymphoid hyperplasia, with enlarged follicles of various sizes and shapes with an irregular distribution. Almost all lymphocytes, except those at the germinal centers, were small.

conclusionGastrointestinal schwannoma is characterized by lymph node swelling. Appendiceal schwannoma may have characteristics, including peritumoral lymph node swelling, similar to other types of gastrointestinal schwannoma such as that in the stomach. Thus, this characteristic can be a diagnostic clue for appendiceal schwannoma.

Indexed as

AppendixLymphadenopathyNeurilemmomaAgedHumansLymph Node ExcisionLymph NodesMaleAppendiceal schwannomaappendiceal tumorCTMRI.schwannomastomach

Identifiers

PMID34102981
PMCPMC8972257

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