Evidence map›Paper›PMID 34102912›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Deep learning-based identification of acute ischemic core and deficit from non-contrast CT and CTA.

Chengyan Wang, Zhang Shi, Ming Yang, Lixiang Huang, Wenxing Fang, Li Jiang, Jing Ding, He Wang

Abstract readComparative Study
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Article
  6. Observational
  7. Cerebral ischemia detection using deep learning techniques.Health information science and systems · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chengyan WangHuman Phenome Institute, Fudan University, Shanghai, China.ORCID 0000-0002-8890-4973
Zhang ShiDepartment of Radiology, Changhai Hospital, Shanghai, China.ORCID 0000-0001-7739-7497
Ming YangNeuroBlem Ltd. Co., Shanghai, China.
Lixiang HuangDepartment of Radiology, Tianjin First Central Hospital, Tianjin, China.
Wenxing FangNeuroBlem Ltd. Co., Shanghai, China.
Li JiangNeuroBlem Ltd. Co., Shanghai, China.
Jing DingDepartment of Neurology, Zhongshan Hospital, Fudan University, Shanghai, China.
He WangHuman Phenome Institute, Fudan University, Shanghai, China.ORCID 0000-0002-2053-9439

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accurate identification of irreversible infarction and salvageable tissue is important in planning the treatments for acute ischemic stroke (AIS) patients. Computed tomographic perfusion (CTP) can be used to evaluate the ischemic core and deficit, covering most of the territories of anterior circulation, but many community hospitals and primary stroke centers do not have the capability to perform CTP scan in emergency situation. This study aimed to identify AIS lesions from widely available non-contrast computed tomography (NCCT) and CT angiography (CTA) using deep learning. A total of 345AIS patients from our emergency department were included. A multi-scale 3D convolutional neural network (CNN) was used as the predictive model with inputs of NCCT, CTA, and CTA+ (8 s delay after CTA) images. An external cohort with 108 patients was included to further validate the generalization performance of the proposed model. Strong correlations with CTP-RAPID segmentations (

Indexed as

AgedBrain IschemiaCerebral AngiographyCerebrovascular CirculationComputed Tomography AngiographyDeep LearningEmergency MedicineFemaleHumansIschemic StrokeMaleMiddle AgedNeural Networks, ComputerPerfusion ImagingPredictive Value of TestsRetrospective StudiesAcute ischemic strokedeep learningdeficitischemic coremultiphase CTA

Identifiers

PMID34102912
PMCPMC8756471

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.