ReviewAtherosclerosis2021
Brain-heart connections in stress and cardiovascular disease: Implications for the cardiac patient.
Review in Atherosclerosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 88 citations in OpenAlex.
- Behavior change intervention targeting physical activity and diet improves stress and sleep.PloS one · 2026Trial
- Altered Neurovascular Coupling Dynamics During Dobutamine-Induced Acute Stress.Brain and behavior · 2026Article
- Psychological Health, Polysocial Risk, and Cardiovascular Health Among Women of Reproductive Age.JACC. Advances · 2026Article
- Brain-heart-eye axis revealed by multi-organ imaging genetics and proteomics.Nature biomedical engineering · 2026Article
- Precision medicine and personalized nursing in cardiovascular disease: clinical applications and frontier developments.Frontiers in cardiovascular medicine · 2026Review
- Mental stress as a trigger of cardiovascular events: A narrative review.European journal of clinical investigation · 2026Review
- The effect of a program for improving positivity skill on perceived stress among patients with chronic heart failure.Journal of education and health promotion · 2026Article
- The less lonely and the more satisfied you are, the merrier is … the heart!European heart journal. Quality of care & clinical outcomes · 2025Article
- Article
- The Overlooked Driver of Hypertension: Mental Stress at the Crossroad of Cardiology and Psychiatry.Current atherosclerosis reports · 2025Review
- Mental health disorders and their impact on cardiovascular health disparities.The Lancet regional health. Europe · 2025Review
- Stress-related genetic factors modify the effect of socioeconomic status on cardiovascular risk.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Parasympathetic response in women with coronary vascular dysfunction during mental stress compared to those with non-cardiac chest pain and reference controls.International journal of cardiology. Heart & vasculature · 2025Article
- Neurophysiological mechanisms underlying cardiovascular adaptations to exercise: A narrative review.Physiological reports · 2025Review
- "Like everybody else": Adolescent perceptions of safe, independent driving with a CHD.Cardiology in the young · 2025Article
- Psychosocial stress and cardiovascular disease.American journal of preventive cardiology · 2025Review
- STEMI under fire: evaluating management and challenges in a warzone amidst the 2023 Israeli conflict.BMC health services research · 2025Article
- Poor Mental Health Status as a Risk Factor and Prognosticator in SMuRF-Less Acute Myocardial Infarction.Journal of clinical medicine · 2025Article
- Toxic stress is associated with cardiovascular disease among younger but not older women in the United States: Results from the research goes red registry.Preventive medicine reports · 2025Article
- Cardiac Response to Stress: Influence of Vortioxetine.Arquivos brasileiros de cardiologia · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 2 countries.
Funding
Abstract
The influence of psychological stress on the physiology of the cardiovascular system, and on the etiology and outcomes of cardiovascular disease (CVD) has been the object of intense investigation. As a whole, current knowledge points to a "brain-heart axis" that is especially important in individuals with pre-existing CVD. The use of acute psychological stress provocation in the laboratory has been useful to clarify the effects of psychological stress on cardiovascular physiology, immune function, vascular reactivity, myocardial ischemia, neurobiology and cardiovascular outcomes. An emerging paradigm is that dynamic perturbations of physiological and molecular pathways during stress or negative emotions are important in influencing cardiovascular outcomes, and that some patient subgroups, such as women, patients with an early-onset myocardial infarction, and patients with adverse psychosocial exposures, may be at especially high risk for these effects. This review summarizes recent knowledge on mind-body connections in CVD among cardiac patients and highlights important pathways of risk which could become the object of future intervention efforts. As a whole, this research suggests that an integrated study of mind and body is necessary to fully understand the determinants and consequences of CVD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.