Evidence map›Paper›PMID 34102320›Full record

ArticleTransfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine2021

Trends in serological markers of transfusion transmissible infections in blood donations at the Bamenda Hospital-based Blood Service, Cameroon.

Moses Samje, Victor N Fondoh, Georges Nguefack-Tsague, Laure K J Kamalieuk, Dora Mbanya, Edward L Murphy, Claude T Tagny

Open access · greenAbstract read
In one paragraph

Article in Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Moses SamjeDepartment of Biomedical Sciences, Faculty of Health Sciences, University of Bamenda, P.O. Box: 39, Bambili, Cameroon. Electronic address: msamje@gmail.com.
Victor N FondohBamenda Regional Hospital, Cameroon.
Georges Nguefack-TsagueDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon.
Laure K J KamalieukDepartment of Biochemistry, University of Bamenda, Cameroon.
Dora MbanyaDepartment of Biomedical Sciences, Faculty of Health Sciences, University of Bamenda, P.O. Box: 39, Bambili, Cameroon; Department of Hematology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon.
Edward L MurphyUniversity of California San Francisco and Blood System Research Institute, USA.
Claude T TagnyDepartment of Hematology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon.
University of Bamenda · CMUniversité de Yaoundé I · CMBamenda University of Science and Technology · CMUniversity of California, San Francisco · US

Funding

Int'l Traineeships in AIDS Prevention Studies (ITAPS)R25MH064712 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LINDAN, CHRISTINA P · 2002 to 2018
$3.4M
Research training in HIV-related transfusion medicine and hematology in South AfricaD43TW010345 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI UTE JENTSCH, EDWARD L MURPHY · 2017 to 2026
$3.0M
International Traineeships in AIDS Prevention Studies (ITAPS)R25MH123256 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTINA P LINDAN · 2020 to 2026
$1.8M
FIC NIH HHS D43 TW010345NIMH NIH HHS R25 MH064712NIMH NIH HHS R25 MH123256
6 · The paper itself

Abstract

objectivesThe rate and trend of transfusion transmissible infections (TTIs) in blood donations from 2012 to 2017 at the Bamenda Regional Hospital Blood Service (BRHBS), Cameroon was assessed. MATERIALS AND

methodsA six-year retrospective study was conducted by reviewing the records of donors. Blood was screened for HIV, hepatitis B, hepatitis C and syphilis. Data was analyzed using IBM SPSS Statistics version 21. Differences in seropositivity rates for the four TTIs were analyzed using Chi

resultsA total of 12,115 blood donations was included in the study and of these, the overall seropositivity rate of the four conventional TTIs markers was 10.5% (n=1,273). Of the seropositive cases, 23.8% (n=303) showed reactivity with at least two of the markers combined. When the markers were assessed individually, HBsAg recorded the highest seropositivity rate (4.7%), followed by anti-HIV and anti-syphilis (2.2%), and then by anti-HCV (1.7%). A significant decrease in the trend of the combined serological markers, HBsAg and anti-syphilis was observed over the years (P≤0.05).

conclusionThere is a decrease in seropositivity rates of TTIs markers in this blood service. Ongoing efforts toward the prevention of these infections is encouraged and should be intensified to improve blood safety.

Indexed as

Hepatitis BHepatitis CHIV InfectionsSyphilisBlood DonorsCameroonHospitalsHumansPrevalenceRetrospective StudiesBlood donationCameroonSero-positivityTransfusion transmissible infections

Identifiers

PMID34102320
PMCPMC8825896
OpenAlexW3170611138

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.