ReviewChest2021
How We Prevent and Treat Delirium in the ICU.
Review in Chest, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Knowledge mapping and research trends on rehabilitation of patients with mechanical ventilation in the ICU from 2005 to 2024: a bibliometric analysis via CiteSpace and Bibliometrix.Frontiers in neurology · 2025Pooled it
- The effect of early mobilization of post-cardiac surgery patients on delirium: a pilot study.European journal of physical and rehabilitation medicine · 2026Trial
- Inflammatory Biomarkers and Delirium Severity in Critically Ill Adults: A Prospective Single-Center Cohort Study.Journal of clinical medicine · 2026Article
- Effects of a non-pharmacological multicomponent intervention on delirium, sleep quality, and total sleep time among emergency intensive care unit patients in South Korea: a non-equivalent control group time-series study.Journal of Korean biological nursing science · 2026Article
- Exploring Current Emergency Medical Services Approaches to Manage Agitated Older Adult Patients: An Analysis of Statewide Protocols.Journal of the American Geriatrics Society · 2026Article
- Impact of Nurses' Knowledge, Self-Efficacy and Clinical Reasoning Competency on Difficulties in Caring for Patients With Delirium in the Intensive Care Unit: A Cross-Sectional Study.Journal of clinical nursing · 2026Article
- Incidence and independent risk factors for postoperative delirium in ICU patients after cardiopulmonary bypass cardiac surgery: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Article
- Comparison of Clinical Outcomes, Diagnosis Timing, or Treatment Differences Based on Motor Subtypes of Delirium in Critically Ill Patients: A Retrospective Study.Psychiatry and clinical psychopharmacology · 2025Article
- Review
- Article
- COVID-19 delirium versus non-COVID-19 delirium in Iran: a computational approach.Acute and critical care · 2025Article
- Association Between Allostatic Load and Delirium in ICU Patients: A Retrospective Analysis of the MIMIC-IV Database.Journal of clinical medicine · 2025Article
- Polypharmacy and anticholinergic burden as risk factors for postoperative delirium in surgical medicine.Zeitschrift fur Gerontologie und Geriatrie · 2025Article
- Implementation of a Quality Improvement Tool "Recover25" to Guide the Care of Patients Experiencing Prolonged Critical Illness: A Mixed-Method Feasibility Study.Critical care explorations · 2025Article
- The Role of Quetiapine in Treating Delirium in Critical Care Settings: A Narrative Review.Journal of clinical medicine · 2025Review
- Guanfacine Use in the ICU for Management of Sedation Weaning.Clinical drug investigation · 2025Review
- Beyond the Lungs: Extrapulmonary Effects of Non-Invasive and Invasive Ventilation Strategies.Journal of clinical medicine · 2025Review
- The impact of perioperative anemia on postoperative delirium after hip fracture surgeries in older adults: a multicenter retrospective cohort study.Frontiers in nutrition · 2025Article
- A Case Report and Review of the Literature of ICU Delirium.Healthcare (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Delirium is a serious and complex problem facing critically ill patients, their families, and the health care system. When delirium develops, it is associated with prolonged hospital stays, increased costs, and long-term cognitive impairment in many patients. This article uses a clinical case to discuss our approach to delirium prevention and treatment in the ICU. We believe that an effective strategy to combat delirium requires implementation and adherence to a pain and sedation protocol as part of bundled care, use of a validated tool to detect delirium when present, and a focus on nonpharmacologic care strategies, including reorientation, early mobility, and incorporating family into care when possible. At present, the evidence does not support the routine administration of medications to prevent or treat delirium. A pharmacologic approach may be needed for agitated delirium, and we discuss our evaluation of the evidence for and against particular medications. Although delirium can be a distressing problem, there is evidence that it can be addressed through careful attention to prevention, detection, and minimizing the long-term impact on patients and their families.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.