Evidence map›Paper›PMID 34102015›Full record

ReviewUnited European gastroenterology journal2021

What gastroenterologists should know about SARS-CoV 2 vaccine: World Endoscopy Organization perspective.

Marco Spadaccini, Lorenzo Canziani, Alessio Aghemo, Ana Lleo, Roberta Maselli, Andrea Anderloni, Silvia Carrara, Alessandro Fugazza, Gaia Pellegatta, Piera Alessia Galtieri and 10 more

Open access · hybridAbstract readReview
In one paragraph

Review in United European gastroenterology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Impact of the COVID-19 pandemic on inflammatory bowel disease care in Taiwan: A multicenter study.Journal of the Formosan Medical Association = Taiwan yi zhi · 2023
    Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 5 countries.

Marco SpadacciniDepartment of Biomedical Sciences, Humanitas University, Rozzano, Italy.ORCID 0000-0003-3909-9012
Lorenzo CanzianiDepartment of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.ORCID 0000-0003-2537-5418
Alessio AghemoDepartment of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
Ana LleoDepartment of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
Roberta MaselliDepartment of Biomedical Sciences, Humanitas University, Rozzano, Italy.
Andrea AnderloniDepartment of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
Silvia CarraraDepartment of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
Alessandro FugazzaDepartment of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.ORCID 0000-0003-0485-4903
Gaia PellegattaDepartment of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
Piera Alessia GaltieriDepartment of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
Cesare HassanDigestive Endoscopy Unit, Nuovo Regina Margherita, Rome, Italy.
David GreenwaldDivision of Gastroenterology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, New York, USA.
Mark PochapinDivision of Gastroenterology and Hepatology, NYU Langone Health, New York, New York, USA.
Michael WallaceDivision of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA.
Prateek SharmaDigestive Endoscopy Unit, Kansas City VA Medical Center, Kansas City, Missouri, USA.
Thomas RoeschDivision of Gastroenterology & Hepatology, University Medical Center Hamburg - Eppendorf, Hamburg, Germany.
Pradeep BhandariDivision of Gastroenterology and Hepatology, Queen Alexandra Hospital, Portsmouth, UK.
Fabian EmuraDivision of Gastroenterology, Universidad de La Sabana, Chía, Colombia.
Gottumukkala S RajuDepartment of Gastroenterology, Hepatology, and Nutrition, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA.
Alessandro RepiciDepartment of Biomedical Sciences, Humanitas University, Rozzano, Italy.
Humanitas University · ITJacksonville College · USKansas City VA Medical Center · USMount Sinai Hospital · USNYU Langone Health · USOspedale Regina Margherita · ITQueen Alexandra Hospital · GBThe University of Texas MD Anderson Cancer Center · USUniversidad de La Sabana · COUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe novel Coronavirus (SARS-CoV-2) has caused almost 2 million deaths worldwide. Both Food and Drug Administration and European Medicines Agency have recently approved the first COVID-19 vaccines, and a few more are going to be approved soon.

methodsSeveral different approaches have been used to stimulate the immune system in mounting a humoral response. As more traditional approaches are under investigation (inactivated virus vaccines, protein subunit vaccines, recombinant virus vaccines), more recent and innovative strategies have been tried (non-replicating viral vector vaccines, RNA based vaccines, DNA based vaccines).

resultsSince vaccinations campaigns started in December 2020 in both the US and Europe, gastroenterologists will be one of the main sources of information regarding SARS-CoV 2 vaccination for patients in their practice, including vulnerable patients such as those with Inflammatory Bowel Disease (IBD), patients with chronic liver disease, and GI cancer patients.

conclusionsThus, we must ourselves be well educated and updated in order to provide unambiguous counseling to these categories of vulnerable patients. In this commentary, we aim to provide a comprehensive review of both approved COVID-19 vaccines and the ones still under development, and explore potential risks, benefits and prioritization of vaccination.

Indexed as

2019-nCoV Vaccine mRNA-1273Ad26COVS1BNT162 VaccineChAdOx1 nCoV-19COVID-19COVID-19 VaccinesGastroenterologyGastrointestinal NeoplasmsHumansInflammatory Bowel DiseasesLiver DiseasesSARS-CoV-22019-nCoV Vaccine mRNA-1273Ad26COVS1BNT162 VaccineChAdOx1 nCoV-19COVID-19 VaccinesNVX-CoV2373 adjuvated lipid nanoparticleCoronavirusendoscopypreventionpublic healthvaccine

Identifiers

PMID34102015
PMCPMC8242672
OpenAlexW3172604951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.