Evidence map›Paper›PMID 34101964›Full record

ReviewObesity reviews : an official journal of the International Association for the Study of Obesity2021

Multicomponent density models for body composition: Review of the dual energy X-ray absorptiometry volume approach.

Steven B Heymsfield, Brooke Smith, Michael Wong, Jonathan Bennett, Cara Ebbeling, Julia M W Wong, Boyd J G Strauss, John Shepherd

Open access · greenAbstract readReview
In one paragraph

Review in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Steven B HeymsfieldPennington Biomedical Research Center, LSU System, Baton Rouge, LA, USA.ORCID 0000-0003-1127-9425
Brooke SmithPennington Biomedical Research Center, LSU System, Baton Rouge, LA, USA.
Michael WongCancer Center, University of Hawaii Cancer Center, Honolulu, HI, USA.
Jonathan BennettCancer Center, University of Hawaii Cancer Center, Honolulu, HI, USA.
Cara EbbelingNew Balance Foundation Obesity Prevention Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
Julia M W WongNew Balance Foundation Obesity Prevention Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
Boyd J G StraussFaculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
John ShepherdCancer Center, University of Hawaii Cancer Center, Honolulu, HI, USA.
University of Hawaiʻi at Mānoa · USBoston Children's Hospital · USPennington Biomedical Research Center · USManchester Academic Health Science Centre · GB

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2005 to 2026
$26.5M
Shape up! KidsR01DK111698 · NIDDK · UNIVERSITY OF HAWAII AT MANOA · PI HEYMSFIELD, STEVEN, SHEPHERD, JOHN ALAN · 2017 to 2021
$3.3M
Optical Body Composition and Health AssessmentR01DK109008 · NIDDK · UNIVERSITY OF HAWAII AT MANOA · PI HEYMSFIELD, STEVEN, SHEPHERD, JOHN ALAN · 2016 to 2020
$3.2M
Quantifying body shape in pediatric clinical researchR01HD103885 · NICHD · UNIVERSITY OF HAWAII AT MANOA · PI HEYMSFIELD, STEVEN, SHEPHERD, JOHN ALAN · 2021 to 2025
$3.1M
NICHD NIH HHS R01 HD103885NIDDK NIH HHS P30 DK040561NIDDK NIH HHS P30 DK072476NIDDK NIH HHS R01 DK109008NIDDK NIH HHS R01 DK111698
6 · The paper itself

Abstract

Accurate and precise body composition estimates, notably of total body adiposity, are a vital component of in vivo physiology and metabolic studies. The reference against which other body composition approaches are usually validated or calibrated is the family of methods referred to as multicomponent "body density" models. These models quantify three to six components by combining measurements of body mass, body volume, total body water, and osseous mineral mass. Body mass is measured with calibrated scales, volume with underwater weighing or air-displacement plethysmography, total body water with isotope dilution, and osseous mineral mass by dual-energy X-ray absorptiometry. Body density is then calculated for use in model as body mass/volume. Studies over the past decade introduced a new approach to quantifying body volume that relies on dual-energy X-ray absorptiometry measurements, an advance that simplifies multicomponent density model development by eliminating the need for underwater weighing or air-displacement plethysmography systems when these technologies are unavailable and makes these methods more accessible to research and clinical programs. This review critically examines these new dual-energy X-ray approaches for quantifying body volume and density, explores their shortcomings, suggests alternative derivation approaches, and introduces ideas for potential future research studies.

Indexed as

Body CompositionPlethysmographyAbsorptiometry, PhotonAdipose TissueAdiposityHumansObesityair displacement plethysmographyisotope dilutionobesityunderwater weighing

Identifiers

PMID34101964
PMCPMC11419666
OpenAlexW3169844601

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.