Evidence map›Paper›PMID 34101951›Full record

ArticleHealth expectations : an international journal of public participation in health care and health policy2021

A scoping review of practice recommendations for clinicians' communication of uncertainty.

Niki M Medendorp, Anne M Stiggelbout, Cora M Aalfs, Paul K J Han, Ellen M A Smets, Marij A Hillen

Abstract readScoping Review
In one paragraph

Article in Health expectations : an international journal of public participation in health care and health policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Early treatment goal uncertainty as a barrier to regional analgesia and respiratory deterioration in traumatic rib fractures: a propensity-weighted analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Observational
  5. Article
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  8. Article
  9. Observational
  10. Article
  11. Bearing the Burdens of Medical Uncertainty.Journal of evaluation in clinical practice · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Uncertainties in the NICU: a scoping review to inform a tailored taxonomy.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  16. Article
  17. Article
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  20. How and why do doctors communicate diagnostic uncertainty: An experimental vignette study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Niki M MedendorpDepartment of Medical Psychology, Amsterdam UMC, Amsterdam Public Health, Amsterdam, The Netherlands.
Anne M StiggelboutMedical Decision Making, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
Cora M AalfsDivision of Biomedical Genetics, Department of Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Paul K J HanCenter for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Portland, ME, USA.
Ellen M A SmetsDepartment of Medical Psychology, Amsterdam UMC, Amsterdam Public Health, Amsterdam, The Netherlands.
Marij A HillenDepartment of Medical Psychology, Amsterdam UMC, Amsterdam Public Health, Amsterdam, The Netherlands.ORCID 0000-0001-5724-7934

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth-care providers increasingly have to discuss uncertainty with patients. Awareness of uncertainty can affect patients variably, depending on how it is communicated. To date, no overview existed for health-care professionals on how to discuss uncertainty.

objectiveTo generate an overview of available recommendations on how to communicate uncertainty with patients during clinical encounters. SEARCH STRATEGY: A scoping review was conducted. Four databases were searched following the PRISMA-ScR statement. Independent screening by two researchers was performed of titles and abstracts, and subsequently full texts. INCLUSION CRITERIA: Any (non-)empirical papers were included describing recommendations for any health-care provider on how to orally communicate uncertainty to patients. DATA EXTRACTION: Data on provided recommendations and their characteristics (eg, target group and strength of evidence base) were extracted. Recommendations were narratively synthesized into a comprehensible overview for clinical practice.

resultsForty-seven publications were included. Recommendations were based on empirical findings in 23 publications. After narrative synthesis, 13 recommendations emerged pertaining to three overarching goals: (a) preparing for the discussion of uncertainty, (b) informing patients about uncertainty and (c) helping patients deal with uncertainty. DISCUSSION AND

conclusionsA variety of recommendations on how to orally communicate uncertainty are available, but most lack an evidence base. More substantial research is needed to assess the effects of the suggested communicative approaches. Until then, health-care providers may use our overview of communication strategies as a toolbox to optimize communication about uncertainty with patients. PATIENT OR PUBLIC CONTRIBUTION: Results were presented to stakeholders (physicians) to check and improve their practical applicability.

Indexed as

CommunicationPhysiciansHealth PersonnelHumansUncertaintyclinicianscommunicationdisclosurehealth carehealth personnelphysician-patient relationsreferral and consultationreviewuncertainty

Identifiers

PMID34101951
PMCPMC8369117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.