Evidence map›Paper›PMID 34101484›Full record

ArticleJCO global oncology2021

Prevalence of

Sudeep Gupta, Senthil Rajappa, Suresh Advani, Amit Agarwal, Shyam Aggarwal, Chanchal Goswami, Satya Dattatreya Palanki, Devavrat Arya, Shekhar Patil, Rohit Kodagali

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in JCO global oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. BRCA Testing in Asian Patients with Ovarian Cancer: Standard Clinical Practice or Mutation Prediction Model?Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. The impact of pathogenicSAGE open medicine · 2024
    Article
  13. Article
  14. Gynaecological Oncology in India: Past, Present and Future.Indian journal of surgical oncology · 2022
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 1 country.

Sudeep GuptaMedical Oncology, Tata Memorial Centre, Mumbai, India.ORCID 0000-0002-6742-6378
Senthil RajappaMedical Oncology, Basavatkaram Indo American Cancer Hospital, Hyderabad, India.
Suresh AdvaniMedical Oncology, Sushrut Hospital, Mumbai, India.
Amit AgarwalMedical Oncology, BLK Superspeciality Hospital, New Delhi, India.ORCID 0000-0001-7221-4292
Shyam AggarwalMedical Oncology, Sir Gangaram Hospital, New Delhi, India.
Chanchal GoswamiMedical Oncology, Medica Superspeciality Hospital, Kolkata, India.
Satya Dattatreya PalankiMedical Oncology, Omega Hospitals, Hyderabad, India.
Devavrat AryaMedical Oncology, Max Institute of Cancer Care, Saket, New Delhi, India.
Shekhar PatilMedical Oncology, HCG Cancer Hospital, Bengaluru, India.
Rohit KodagaliMedical Affairs, AstraZeneca Pharma India Ltd, Bangalore, India.ORCID 0000-0002-6066-8219
Tata Memorial Hospital · INAstraZeneca (India) · INBLK Super Speciality Hospital · INBombay Hospital · INCancer Hospital and Research Institute · INHCG Cancer Hospital · INMaxCure Hospitals · INMax Healthcare · INSir Ganga Ram Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere are deficient data on prevalence of germline mutations in breast cancer susceptibility genes 1 and 2 (

methodsThis prospective, cross-sectional, noninterventional study in nine Indian centers included patients with newly diagnosed or relapsed epithelial ovarian, primary peritoneal, or fallopian tube cancer. The primary objective was to assess the prevalence of

resultsBetween March 2018 and December 2018, 239 patients with a median age of 53.0 (range, 23.0-86.0 years) years were included, of whom 203 (84.9%) had newly diagnosed disease, 36 (15.1%) had family history of ovarian or breast cancer, and 159 (66.5%) had serous subtype of epithelial ovarian cancer. Germline pathogenic or likely pathogenic mutations in

conclusionThere is a high prevalence of pathogenic or likely pathogenic germline

Indexed as

Fallopian Tube NeoplasmsOvarian NeoplasmsAdultAgedAged, 80 and overBRCA1 ProteinBRCA2 ProteinCross-Sectional StudiesFemaleHumansIndiaMiddle AgedMutationPrevalenceProspective StudiesYoung AdultBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, human

Identifiers

PMID34101484
PMCPMC8457852
OpenAlexW3171097935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.