Evidence map›Paper›PMID 34101073›Full record

ArticleInflammation2021

Penta-acetyl Geniposide Suppresses Migration, Invasion, and Inflammation of TNF-α-Stimulated Rheumatoid Arthritis Fibroblast-Like Synoviocytes Involving Wnt/β-Catenin Signaling Pathway.

Li Cai, Yu-Rong Mu, Ming-Ming Liu, Meng-Yuan Zhou, Bo Meng, Fang-Yuan Liu, Rong Li

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Immunomodulatory and growth-promoting effects ofFrontiers in veterinary science · 2025
    Article
  5. Article
  6. Fullerenol inhibits tendinopathy by alleviating inflammation.Frontiers in bioengineering and biotechnology · 2023
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Li CaiInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui Province, People's Republic of China.
Yu-Rong MuInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui Province, People's Republic of China.
Ming-Ming LiuInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui Province, People's Republic of China.
Meng-Yuan ZhouInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui Province, People's Republic of China.
Bo MengInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui Province, People's Republic of China.
Fang-Yuan LiuInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui Province, People's Republic of China.
Rong LiInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui Province, People's Republic of China. aydlirong@163.com.ORCID http://orcid.org/0000-0002-4672-7868
Anhui Medical University · CN

Funding

National Natural Science Foundation of China 81102273National Natural Science Foundation of China 81972040Open Project Program of Inflammation and Immune Mediated Diseases Laboratory of Anhui Province IMMDL202001Program for Outstanding Young Talents of Higher Education Institution of Anhui Province gxyqZD2016045
6 · The paper itself

Abstract

We previously reported that penta-acetyl geniposide ((Ac)

Indexed as

AnimalsAnti-Inflammatory AgentsAntirheumatic AgentsArthritis, ExperimentalArthritis, RheumatoidCell LineCell MovementFibroblastsHumansInflammation MediatorsIridoid GlucosidesMaleMatrix MetalloproteinasesRatsRats, Sprague-DawleySynoviocytesAnti-Inflammatory AgentsAntirheumatic AgentsInflammation MediatorsIridoid GlucosidesMatrix Metalloproteinasespentaacetyl geniposideTumor Necrosis Factor-alphafibroblast-like synoviocyteinflammationmigrationpenta-acetyl geniposiderheumatoid arthritisWnt/β-catenin signaling pathway

Identifiers

PMID34101073
OpenAlexW3168457116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.