Evidence map›Paper›PMID 34101055›Full record

ArticleClinical and experimental medicine2022

Increased TIM-3

Qing Luo, Yunyuan Kong, Biqi Fu, Xue Li, Qingshui Huang, Zikun Huang, Junming Li

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. The proportion of CD161 on CD56Immunity, inflammation and disease · 2024
    Article
  12. Article
  13. Rapamycin relieves lupus nephritis by regulating TIM-3 and CD4Central-European journal of immunology · 2022
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qing Luo *Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.ORCID http://orcid.org/0000-0001-7559-5174
Yunyuan Kong *Outpatient Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Biqi FuDepartment of Rheumatology, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Xue LiDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Qingshui HuangDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Zikun HuangDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China. 491353062@qq.com.
Junming LiDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China. lisir361@163.com.
Nanchang University · CN

Funding

Jiangxi Provincial Natural Science Foundation of China 20202BABL206044Key Research and Development Program of Jiangxi Province 20181BBG70013Natural Science Foundation of Jiangxi Province 20151BAB215031Natural Science Foundation of Jiangxi Province 20171BAB205113the Foundation for Distinguished Young Scientists of Jiangxi Province of china 20171BCB23087the National Natural Science Foundation of China 81360459the National Natural Science Foundation of China 81660277the National Natural Science Foundation of China 81760297the Science and Technology Plan Project of the Education Department of Jiangxi Province 170008the Science and Technology Project of Health and Family Planning Commission of Jiangxi Province of China 20165094
6 · The paper itself

Abstract

It is well established that natural killer (NK) cells are dysregulated in systemic lupus erythematosus (SLE) patients. However, the functions of NK cells and the mechanisms regulated by them in SLE remain incompletely understood. Patients with SLE were recruited from The First Affiliated Hospital of Nanchang University, and their clinical characteristics and treatments were recorded. The expression levels of T cell immunoglobulin mucin-3 (TIM-3) and programmed cell death protein 1 (PD-1) on NK cells were examined using flow cytometry. The correlations between the increase in TIM-3

Indexed as

Hepatitis A Virus Cellular Receptor 2Lupus Erythematosus, SystemicFlow CytometryHumansKiller Cells, NaturalProgrammed Cell Death 1 ReceptorHAVCR2 protein, humanHepatitis A Virus Cellular Receptor 2PDCD1 protein, humanProgrammed Cell Death 1 ReceptorNatural killer cellsProgrammed cell death protein 1Systemic lupus erythematosusT cell immunoglobulin mucin-3

Identifiers

PMID34101055
PMCPMC8863699
OpenAlexW3169755518

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.