Evidence map›Paper›PMID 34101008›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2022

The use of melatonin for auditory brainstem response audiometry in children with comorbidities.

Caroline Struijk, Nicolien van der Poel, Isabel Blommaerts, Tine Boiy, Anouk Hofkens-Van Den Brandt, Kaat Van Den Brande, Olivier Vanderveken, Hanne Vermeersch, An Boudewyns

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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Caroline Struijk *Department of Orthopedic Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium. Struijk.caroline@gmail.com.ORCID http://orcid.org/0000-0002-0203-607X
Nicolien van der Poel *Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, Edegem, 2650, Antwerp, Belgium.
Isabel BlommaertsDepartment of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, Edegem, 2650, Antwerp, Belgium.
Tine BoiyDepartment of Pediatrics, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium.
Anouk Hofkens-Van Den BrandtDepartment of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, Edegem, 2650, Antwerp, Belgium.
Kaat Van Den BrandeDepartment of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, Edegem, 2650, Antwerp, Belgium.
Olivier VandervekenDepartment of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, Edegem, 2650, Antwerp, Belgium.
Hanne VermeerschDepartment of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, Edegem, 2650, Antwerp, Belgium.
An BoudewynsDepartment of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, Edegem, 2650, Antwerp, Belgium.
University of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this study, the efficacy and feasibility of melatonin in young children with and without comorbidities, undergoing auditory brainstem response audiometry (ABR) was evaluated. The aim of this study was primarily to evaluate the use of melatonin for ABR investigations in children with comorbidities. Second, the efficacy of melatonin was evaluated based on several factors like sleep-onset latency, sleep duration, frequency of awakenings as well as adverse events.

methodsClick-induced ABR tests were performed at the outpatient clinic between January, 2018 and August, 2020. Investigations were considered successful when binaural testing was completed. A dose of melatonin depending on age, 5 mg for children younger than 6 years and 10 mg if older than 6 years, was administered after placement of electrodes.

results131 children were included in this study. 87% of all ABR investigations were performed successfully. Comorbidities such as neurodevelopmental disorders or developmental delays were present in 70% of all children. There was no significant difference in age (p = 0.36) or gender (p = 0.97) between the success and failed group. In addition, comorbidities were equally distributed between both groups. Mean sleep duration was 38 (SD 21) min and sleep-onset latency was 28 (SD 20) min No adverse events were documented.

conclusionMelatonin is effective for ABR examinations in infants and children with and without comorbidities. Furthermore, it allows for sequential testing in those at risk for progressive hearing loss. Clear instructions to caregivers and expertise of audiologists are a prerequisite for optimal outcomes.

Indexed as

Hearing LossMelatoninAudiometryAuditory ThresholdChildChild, PreschoolEvoked Potentials, Auditory, Brain StemHumansInfantMelatoninBrainstem-evoked response audiometryChildrenHearing testInfantsMelatonin

Identifiers

PMID34101008
OpenAlexW3168631287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.