Evidence map›Paper›PMID 34100660›Full record

ArticleJournal of feline medicine and surgery2022

Clinical features, treatment and outcome of discospondylitis in cats.

Sergio A Gomes, Laurent S Garosi, Sebastien Behr, Cristina Toni, Joana Tabanez, Clare Rusbridge, Mike Targett, Mark Lowrie

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Gabapentin: Clinical Use and Pharmacokinetics in Dogs, Cats, and Horses.Animals : an open access journal from MDPI · 2023
    Review
  3. Computed tomography features of discospondylitis in dogs.Journal of veterinary internal medicine · 2022
    Article
  4. Frontiers in veterinary science · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Sergio A GomesDovecote Veterinary Hospital, Castle Donington, Derby, UK.ORCID 0000-0002-9452-7262
Laurent S GarosiVet Oracle Teleneurology, Diss, UK.
Sebastien BehrNeurology/Neurosurgery Service, Willows Veterinary Centre and Referral Centre, Solihull, West Midlands, UK.
Cristina ToniNeurology/Neurosurgery Service, Willows Veterinary Centre and Referral Centre, Solihull, West Midlands, UK.ORCID 0000-0002-8003-1784
Joana TabanezFitzpatrick Referrals, Godalming, Surrey, UK.
Clare RusbridgeFitzpatrick Referrals, Godalming, Surrey, UK.ORCID 0000-0002-3366-2110
Mike TargettSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Leicestershire, UK.
Mark LowrieDovecote Veterinary Hospital, Castle Donington, Derby, UK.ORCID 0000-0002-4993-589X
Willows Veterinary Centre and Referral Service · GBGuildford Hospital · GBOracle (United Kingdom) · GBUniversity of Nottingham · GBUniversity of Surrey · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere is a paucity of information on feline discospondylitis. This study aimed to describe the signalment, clinical and laboratory findings, aetiological agents, treatment and outcome in cats affected by discospondylitis.

methodsThis was a retrospective review of the medical records of cats diagnosed with discospondylitis at four referral institutions.

resultsA total of 17 cats were identified. Most were domestic shorthair cats (76.5%) and male (58.8%), with a median age of 9 years (range 0.9-14) and a median duration of clinical signs of 3 weeks (range 0.3-16). All cats presented with spinal hyperaesthesia; 3/17 had pyrexia. Neurological dysfunction was found in 64.7% of cats, which was indicative of a T3-L3 or L4-S2 spinal segment, associated nerve root or associated nerve neurolocalisation. Haematology, serum biochemistry and urinalysis revealed occasional inconsistent non-specific changes. All cats underwent urine culture; 9/17 cats also had a distinct tissue cultured. Positive bacterial cultures were obtained in two cats (11.8%) for CONCLUSIONS AND RELEVANCE: Feline discospondylitis is uncommon and no obvious signalment predisposition was found in this study. Spinal hyperaesthesia was universally present, with neurological dysfunction also highly prevalent. Bacterial culture was unrewarding in most cases. Amoxicillin-clavulanic acid or cephalosporins are reasonable choices for first-line antibiotics. Prognosis was favourable, with no long-term evidence of recurrence in cats on sustained antibiotic therapy, for a mean duration of 3 months.

Indexed as

Cat DiseasesDiscitisAnimalsAnti-Bacterial AgentsCatsFemaleHyperesthesiaMaleRetrospective StudiesTreatment OutcomeAnti-Bacterial AgentsabscessBacteriadiscitisinfectionmyelopathypyogenicspinal

Identifiers

PMID34100660
PMCPMC10812237
OpenAlexW3173127836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.