ArticlemSystems2021
Projection of Gut Microbiome Pre- and Post-Bariatric Surgery To Predict Surgery Outcome.
Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gut microbiome alterations and their clinical and biological implications in ovarian cancer: a systematic review.Frontiers in oncology · 2025Pooled it
- Short-term gut microbiota's shift after laparoscopic Roux-en-Y vs one anastomosis gastric bypass: results of a multicenter randomized control trial.Surgical endoscopy · 2024Trial
- Gut Microbiota-Derived Extracellular Vesicles in Patients With Obesity Undergoing Gastric Bypass Surgery.Molecular microbiology · 2026Article
- Impact of gut microbiome on outcomes following endoscopic interventions in gastrointestinal disease.World journal of gastrointestinal endoscopy · 2025Article
- Predicting pregnancy at the first year following metabolic-bariatric surgery: development and validation of machine learning models.Surgical endoscopy · 2025Article
- Neurobiological and Microbiota Alterations After Bariatric Surgery: Implications for Hunger, Appetite, Taste, and Long-Term Metabolic Health.Brain sciences · 2025Review
- Bringing gut microbiota into the spotlight of clinical research and medical practice.World journal of clinical cases · 2024Article
- Mechanisms of bariatric surgery for weight loss and diabetes remission.Journal of diabetes · 2023Review
- Article
- The gut microbiota in obesity and weight management: microbes as friends or foe?Nature reviews. Endocrinology · 2023Review
- Bile acids and microbes in metabolic disease.World journal of gastroenterology · 2022Review
- Integrative web cloud computing and analytics using MiPair for design-based comparative analysis with paired microbiome data.Scientific reports · 2022Article
- Role of the Gut Microbiome and Bile Acids.Deutsches Arzteblatt international · 2022Article
- Metabolic Profile and Metabolite Analyses in Extreme Weight Responders to Gastric Bypass Surgery.Metabolites · 2022Article
- Microbiota and body weight control: Weight watchers within?Molecular metabolism · 2022Review
- Using the microbiome in clinical practice.Microbial biotechnology · 2022Article
- Gut microbiome and microbial metabolites in NAFLD and after bariatric surgery: Correlation and causality.Frontiers in microbiology · 2022Review
- Gut microbiota and obesity: New insights.Frontiers in nutrition · 2022Review
- Ordering taxa in image convolution networks improves microbiome-based machine learning accuracy.Gut microbesArticle
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
Bariatric surgery is often the preferred method to resolve obesity and diabetes, with ∼800,000 cases worldwide yearly and high outcome variability. The ability to predict the long-term body mass index (BMI) change following surgery has important implications for individuals and the health care system in general. Given the tight connection between eating habits, sugar consumption, BMI, and the gut microbiome, we tested whether the microbiome before any treatment is associated with different treatment outcomes, as well as other intakes (high-density lipoproteins [HDL], triglycerides, etc.). A projection of the gut microbiome composition of obese (sampled before and after bariatric surgery) and lean patients into principal components was performed, and the relation between this projection and surgery outcome was studied. The projection revealed three different microbiome profiles belonging to lean, obese, and obese individuals who underwent bariatric surgery, with the postsurgery microbiome more different from the lean microbiome than the obese microbiome. The same projection allowed for a prediction of BMI loss following bariatric surgery, using only the presurgery microbiome. The microbial changes following surgery were an increase in the relative abundance of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.