Evidence map›Paper›PMID 34100577›Full record

ArticleSensors and actuators. B, Chemical1996

Frequency-domain lifetime measurements and sensing in highly scattering media.

Henryk Szmackinski, Joseph R Lakowicz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors and actuators. B, Chemical, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Intensity measurements in scattering media.Sensors and actuators. B, Chemical · 1999
    Article
  3. Article
  4. Article
  5. A water-soluble luminescence oxygen sensor.Photochemistry and photobiology · 1998
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Henryk SzmackinskiCenter for Fluorescence Spectroscopy, Department of Biological Chemistry, University of Maryland at Baltimore, School of Medicine, 108 N. Greene Street, Baltimore, MD 21201, USA
Joseph R LakowiczCenter for Fluorescence Spectroscopy, Department of Biological Chemistry, University of Maryland at Baltimore, School of Medicine, 108 N. Greene Street, Baltimore, MD 21201, USA

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI CHEUNG, HERBERT C · 1993 to 2006
$7.4M
NCRR NIH HHS P41 RR008119
6 · The paper itself

Abstract

For clinical chemistry, or for non-invasive sensing through skin, it is often necessary to obtain quantitative information in highly scattering media. We describe two simple methods for fluorescence lifetime measurements in highly scattering media, and in particular in an intralipid suspension. Lifetimes can be measured using an intensity decay law that accounts for the time delays and pulse-broadening effects of multiple light-scattering events in the intralipid. Alternatively, the phase and modulation measurements can be performed relative.to a reference fluorophore with a known lifetime. These approaches provide reliable lifetime data for a pH-sensitive fluorophore contained within a microeuvette 4 mm under the surface of the intralipid suspension. Fluorescence lifetime-based sensing is now recognized as a valuable methodology in clinical and analytical chemistry, and the possibility of lifetime-based sensing in turbid media has been demonstrated.

Indexed as

Clinical chemistryFluorescenceFluorescence spectroscopyFrequency-domain fluorescenceLifetime-based sensingNon-invasive sensingPhoton migrationpH sensingTime-resolved fluorescence

Identifiers

PMID34100577
PMCPMC8147913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.