ReviewJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2021
Anastomotic Leak: Toward an Understanding of Its Root Causes.
Review in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06630910 (New Technique of End to Side Two Layered and Stented Duct to Mucosa Pancreaticojejunostomy With Omental Wrapping During Whipple Operation), which is not on this map. Cited by 31 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
New Technique of End to Side Two Layered and Stented Duct to Mucosa Pancreaticojejunostomy With Omental Wrapping During Whipple Operation
Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Does laparoscopic-assisted transanal endorectal pull-through improve outcomes compared with transanal endorectal pull-through in Hirschsprung disease? A systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
- The impact of the number of stapler firings on anastomotic leakage in minimally invasive rectal surgery: risk factor or technical marker of complexity? A systematic review, meta‑analysis, and metaregression.Techniques in coloproctology · 2026Pooled it
- Left colectomy for diverticular disease: systematic review and meta-analysis comparing robotic and laparoscopic resections.Techniques in coloproctology · 2025Pooled it
- Robotic versus laparoscopic colectomy for transverse colon cancer: a systematic review and meta-analysis.International journal of colorectal disease · 2025Pooled it
- New technique of end to side two layered and stented duct to mucosa pancreaticojejunostomy with omental wrapping during Whipple operation.BMC surgery · 2025Trial
- Circular stapler platform and the risk of anastomotic leakage after elective left colectomy and high anterior resection.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Observational
- Advancing early diagnosis of colorectal anastomotic leakage using drain fluid biochemical analysis.Scientific reports · 2026Article
- The Predictive Value of Clinical and Systemic Inflammatory Biomarkers in Emergency Colic Cancer Surgery: A Retrospective Study.Journal of clinical medicine · 2026Article
- Mechanomedicine in digestive surgery: a theranostic framework integrating mechanical diagnostics and therapeutic modulation across the perioperative continuum.Theranostics · 2026Review
- Extracellular Matrix Hydrogel Reduces Anastomotic Leaks in a Rodent Model of Rectal Anastomosis.The Journal of surgical research · 2025Article
- Building a risk prediction model for anastomotic leakage postoperative low rectal cancer based on Lasso-Logistic regression.BMC gastroenterology · 2025Article
- Development of a machine learning-based tension measurement method in robotic surgery.Surgical endoscopy · 2025Article
- Layer-specific molecular signatures of colon anastomotic healing and leakage in mice.Molecular medicine (Cambridge, Mass.) · 2025Article
- Efficacy of a Shortened Oral Antibiotic Bowel Decontamination in Minimally Invasive Surgery for Diverticular Disease.Visceral medicine · 2025Article
- The usefulness of fluorescence in decision-making strategy during bariatric and metabolic surgery.Langenbeck's archives of surgery · 2025Observational
- Development of a Clinical Framework-Anastomotic Leakage Prediction Score (CF-ALPS) After Colorectal Surgery.Diagnostics (Basel, Switzerland) · 2025Article
- A new oblique-to-side esophagogastric anastomosis approach reduces the incidence of postoperative anastomotic leak after esophagectomy for esophageal carcinoma: a propensity score-matched retrospective study.American journal of cancer research · 2025Article
- Non-Thermal Atmospheric Pressure Plasma as an Adjunct to Intestinal Anastomosis: A Pilot Study on Preventing Anastomotic Leaks.Life (Basel, Switzerland) · 2024Article
- [Modern approaches and technologies to prevent anastomotic leakage in the gastrointestinal tract].Chirurgie (Heidelberg, Germany) · 2024Article
- Long-Term Efficacy and Safety of Adhesion Prevention Agents in Abdominal and Pelvic Surgeries: A Systematic Review.Cureus · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundWhen an anastomotic leak is discussed at a typical surgical morbidity and mortality conference, it is often presented as a due to an error in surgical technique involving ischemia, tension, or device failure. Here we assert that without direct visual analysis of the leak site and its tissue histology, an ex post facto claim that an anastomotic leak is due to an error in surgical technique remains speculative.
methodsThe arguments and rationale used to conclude that an anastomotic leak is due to an error in surgical technique are critically reviewed and assessed for their validity.
resultsNo case series or literature exists in which a root cause analysis has been carried out with visual and tissue level evidence to determine the root cause(s) of an anastomotic leak.
conclusionsAt the individual case level, declaring that an anastomotic leak is due to an error in surgical technique without clear and compelling evidence either visually and/or at the tissue level to substantiate such a claim remains speculative.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.