Evidence map›Paper›PMID 34100118›Full record

ArticleArchives of osteoporosis2021

A country-specific FRAX model for Botswana.

M Kebaetse, S Nkhwa, M Mogodi, J Masunge, Y P Gureja, M Ramabu, T Mmopelwa, I Sharif, A Orford, N C Harvey and 4 more

Abstract read
In one paragraph

Article in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Romosozumab efficacy and safety in European patients enrolled in the FRAME trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Trial
  2. On the development and application of country-specific FRAX models in Latin America.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  3. Review
  4. Race-specific FRAX models are evidence-based and support equitable care: a response to the ASBMR Task Force report on Clinical Algorithms for Fracture Risk.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

M KebaetseFaculty of Medicine, University of Botswana, Gaborone, Botswana.
S NkhwaFaculty of Medicine, University of Botswana, Gaborone, Botswana.
M MogodiFaculty of Medicine, University of Botswana, Gaborone, Botswana.
J MasungeFaculty of Medicine, University of Botswana, Gaborone, Botswana.
Y P GurejaPrincess Marina Hospital, Gaborone, Botswana.
M RamabuPrincess Marina Hospital, Gaborone, Botswana.
T MmopelwaGaborone Private Hospital, Gaborone, Botswana.
I SharifBokamoso Private Hospital, Gaborone, Botswana.
A OrfordGaborone Private Hospital, Gaborone, Botswana.
N C HarveyMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
E V McCloskeyCentre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.
J A CauleyDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
J A KanisCentre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK. w.j.pontefract@sheffield.ac.uk.
H JohanssonCentre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHip fracture rates in Botswana were used to create a FRAX® model for fracture risk assessment.

objectiveThis paper describes the development and characteristics of a country-specific FRAX model for Botswana.

methodsAge-specific and sex-specific incidence of hip fracture and national mortality rates was incorporated into a FRAX model for Botswana. Ten-year fracture probabilities were compared with those from African countries having a FRAX model and African Americans from the USA.

resultsThe probabilities of hip fracture and major osteoporotic fracture were low compared with those from South Africa (Black and Coloured) and US Blacks. Probabilities were marginally higher than for Tunisia.

conclusionThe creation of a FRAX model is expected to help guide decisions about the prevention and treatment of fragility fractures in Botswana.

Indexed as

Hip FracturesOsteoporotic FracturesBotswanaFemaleHumansMaleRisk AssessmentRisk FactorsSouth AfricaBotswanaEpidemiologyFracture probabilityFRAXHip fractureMajor osteoporotic fracture

Identifiers

PMID34100118
PMCPMC8184541

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.