ArticlemedRxiv : the preprint server for health sciences2021
IL10RB as a key regulator of COVID-19 host susceptibility and severity.
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Article in medRxiv : the preprint server for health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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30 authors at 11 institutions in 2 countries.
Georgios VoloudakisDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Gabriel HoffmanDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Sanan VenkateshDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Kyung Min LeeDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Kristina DobrindtDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
James M VicariDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Wen ZhangDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Noam D BeckmannDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Shan JiangDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Daisy HoaglandDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Jiantao BianDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Lina GaoDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
André CorveloDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Kelly ChoDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Jennifer S LeeDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Sudha K IyengarDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Shiuh-Wen LuohDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Schahram AkbarianDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Robert StrikerDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Themistocles L AssimesDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Eric E SchadtDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Miriam MeradDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Benjamin R tenOeverDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Alexander W CharneyDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Mount Sinai COVID-19 Biobank
VA Million Veteran Program COVID-19 Science Initiative
Kristen J BrennandDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Julie A LynchDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
John F FullardDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Panos RoussosDepartment of Psychiatry (G.V., S.V., K.D., J.V., W.Z., S.J., S.A., A.W.C., K.J.B., P.R.), Pamela Sklar Division of Psychiatric Genomics (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., A.W.C., J. F.F., K.J.B., P.R.), Friedman Brain Institute (G.V., G.H., S.V., K.D., J.V., W.Z., S.J., S.A., J.F.F., K.J.B., P.R.), Department of Genetics and Genomic Science (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A., E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Icahn Institute for Data Science and Genomic Technology (G.V., G.H., S.V., K.D., J.V., W.Z., N.D.B., S.J., S.A, E.E.S., A.W.C., J.F.F., K.J.B., P.R.), Nash Family Department of Neuroscience (K.D., S.A, A.W.C., K.J.B.), Department of Microbiology (D.H., B.R.T.), Virus Engineering Center for Therapeutics and Research (D.H., B.R.T.), Global Health and Emerging Pathogens Institute (D.H., B.R.T.), Mount Sinai Clinical Intelligence Center (N.D.B., A.W.C.), Department of Oncological Sciences (M.M.), Precision Immunology Institute (M.M.) and Tisch Cancer Institute (M.M.) of the Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; the Mental Illness Research, Education, and Clinical Center (VISN 2 South) of the James J. Peters VA Medical Center (G.V., S.V., P.R.), Bronx, NY 10468, USA; VA Informatics and Computing Infrastructure (K.M.L., J.B., J.A.L.), VA Salt Lake City Health Care System, Salt Lake City, UT; Department of Psychiatry (K.D., K.J.B.) of the Yale University, New Haven, CT 06511, USA; Division of Epidemiology (J.B., J.A.L.), University of Utah, Salt Lake City, UT 84108, USA; New York Genome Center (A.C.), New York, NY 10013, USA; Biostatistics Shared Resources (L.G.) and Department of Medicine (S.-W.L.), Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97229, USA; VA Boston Healthcare System (K.C.), Boston, MA, USA; Division of Aging (K.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine (J.S.L., T.L.A.), Stanford University School of Medicine, Stanford, CA, 94304, USA; VA Palo Alto Health Care System (J.S.L., T.L.A.), Palo Alto, CA, 94304, USA; Department of Population and Quantitative Health Sciences (S.K.I), and Department of Genetics and Genome Sciences (S.K.I.), School of Medicine, Case Western Reserve University, Cleveland, OH 44106; VA Northeast Ohio Healthcare System (S.K.I.), Cleveland VA Medical Center, Cleveland, OH 44106; VA Portland Health Care System (S.-W.L.), Portland, OR 97239; Division of Infectious Diseases (R.S.), Department of Medicine, University of Wisconsin, Madison, WI; William S. Middleton Memorial Veterans Hospital (R.S.), Madison, WI 53705; and Sema4 (E.E.S.), Stamford, CT 06902, USA.
Allen Institute for Brain Science · USJisc · GBOregon Health & Science University · USUniversity of Utah · USVA Palo Alto Health Care System · USBrigham and Women's Hospital · USNew York Genome Center · USSema4 (United States) · USUniversity of Wisconsin–Madison · USVA Northeast Ohio Healthcare System · USVA Salt Lake City Healthcare System · US
Funding
Understanding the molecular mechanisms that contribute to neuropsychiatric symptoms in Alzheimer DiseaseR01AG067025 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FINKBEINER, STEVEN M, HAROUTUNIAN, VAHRAM · 2019 to 2023
$11.8MHigher Order Chromatin and Genetic Risk for Alzheimer's DiseaseR01AG050986 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ROUSSOS, PANAGIOTIS · 2015 to 2025
$11.2MUnderstanding the protective and neuroinflammatory role of human brain immune cells in Alzheimer DiseaseR01AG065582 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HAROUTUNIAN, VAHRAM, ROUSSOS, PANAGIOTIS · 2020 to 2024
$9.9MThe 3D genome in transcriptional regulation across the postnatal life span, with implications for schizophrenia and bipolar disorderU01MH116442 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI AKBARIAN, SCHAHRAM, DRACHEVA, STELLA · 2018 to 2022
$5.9MRisk genetic variants and cis regulation of gene expression in Bipolar DisorderR01MH109677 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ROUSSOS, PANAGIOTIS · 2016 to 2020
$4.6MFunctional genomic resource and integrative model of dopaminergic circuitry associated with psychiatric diseaseU01DA048279 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI AKBARIAN, SCHAHRAM, BRENNAND, KRISTEN JENNIFER · 2019 to 2023
$3.5MCharacterizing and targeting subphenotypes of schizophrenia and bipolar disorder via individually imputed tissue and cell-type specific transcriptomesK08MH122911 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI VOLOUDAKIS, GEORGIOS · 2020 to 2023
$770kLarge-scale transcriptome and epigenome association analysis across multiple traitsI01BX004189 · VA · JAMES J PETERS VA MEDICAL CENTER · PI Panagiotis Roussos · 2019 to 2026
–Dissecting Cis Regulation of Gene Expression in SchizophreniaI01BX002395 · VA · JAMES J PETERS VA MEDICAL CENTER · PI ROUSSOS, PANAGIOTIS · 2014 to 2022
–BLRD VA I01 BX002395BLRD VA I01 BX004189NIA NIH HHS R01 AG050986NIA NIH HHS R01 AG065582NIA NIH HHS R01 AG067025NIDA NIH HHS U01 DA048279NIMH NIH HHS K08 MH122911NIMH NIH HHS R01 MH109677NIMH NIH HHS U01 MH116442
Abstract
backgroundRecent efforts have identified genetic loci that are associated with coronavirus disease 2019 (COVID-19) infection rates and disease outcome severity. Translating these genetic findings into druggable genes and readily available compounds that reduce COVID-19 host susceptibility is a critical next step.
methodsWe integrate COVID-19 genetic susceptibility variants, multi-tissue genetically regulated gene expression (GReX) and perturbargen signatures to identify candidate genes and compounds that reverse the predicted gene expression dysregulation associated with COVID-19 susceptibility. The top candidate gene is validated by testing both its GReX and observed blood transcriptome association with COVID-19 severity, as well as by
resultsWe identify
conclusionsWe establish an integrative data-driven approach for gene target prioritization. We identify and validate
Identifiers
What OpenQuestion holds
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