Evidence map›Paper›PMID 34100027›Full record

ArticlemedRxiv : the preprint server for health sciences2021

Immune transcriptomes from hospitalized patients infected with the SARS-CoV-2 variants B.1.1.7 and B.1.1.7 carrying the E484K escape mutation.

Hye Kyung Lee, Ludwig Knabl, Ludwig Knabl, Manuel Wieser, Anna Mur, August Zabernigg, Jana Schumacher, Norbert Kaiser, Priscilla A Furth, Lothar Hennighausen

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Hye Kyung Lee *National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, MD 20892, USA.
Ludwig Knabl *TyrolPath, Zams, Austria.
Ludwig KnablKrankenhaus St. Vinzenz, Zams, Austria.
Manuel WieserTyrolPath, Zams, Austria.
Anna MurDivision of Internal Medicine, Krankenhaus Kufstein, Kufstein, Austria.
August ZaberniggDivision of Internal Medicine, Krankenhaus Kufstein, Kufstein, Austria.
Jana SchumacherDivision of Internal Medicine, Krankenhaus St. Johann, St. Johann, Austria.
Norbert KaiserDivision of Internal Medicine, Krankenhaus St. Johann, St. Johann, Austria.
Priscilla A FurthDepartments of Oncology & Medicine, Georgetown University, Washington, DC, USA.
Lothar HennighausenNational Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, MD 20892, USA.
Geriatrische Gesundheitszentren · ATNational Institute of Diabetes and Digestive and Kidney Diseases · USGeorgetown University · USHospital of the Brothers of St. John of God · ATUniversity of Applied Sciences Kufstein · AT

Funding

Immune transcriptomes of SARS-CoV-2 infected populationsZIADK075155 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI HENNIGHAUSEN, LOTHAR · 2020 to 2024
$8.1M
6 · The paper itself

Abstract

Fast-spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) energize the COVID-19 pandemic. B.1.1.7 (VOC-202012/01) has become the predominant variant in many countries and a new lineage (VOC-202102/02) harboring the E484K escape mutation in the B.1.1.7 background emerged in February 2021

Identifiers

PMID34100027
PMCPMC8183026
OpenAlexW3164861465

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.