Evidence map›Paper›PMID 34099879›Full record

ArticleCommunications biology2021

Metabolic control of daily locomotor activity mediated by tachykinin in Drosophila.

Sang Hyuk Lee, Eunjoo Cho, Sung-Eun Yoon, Youngjoon Kim, Eun Young Kim

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  7. iScience · 2025
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  8. Review
  9. Gut-Brain Dialogues in Fruit Fly (Current drug targets · 2025
    Review
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  12. The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  13. TheMolecules and cells · 2022
    Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sang Hyuk LeeDepartment of Biomedical Sciences, Ajou University Graduate School of Medicine, 164 Worldcup-ro, Suwon, Kyunggi-do, Republic of Korea.ORCID 0000-0002-4414-8176
Eunjoo ChoDepartment of Biomedical Sciences, Ajou University Graduate School of Medicine, 164 Worldcup-ro, Suwon, Kyunggi-do, Republic of Korea.
Sung-Eun YoonKorea Drosophila Resource Center, GIST, Oryong-dong, Buk-gu, Gwangju, Republic of Korea.ORCID 0000-0002-9162-2352
Youngjoon KimKorea Drosophila Resource Center, GIST, Oryong-dong, Buk-gu, Gwangju, Republic of Korea.ORCID 0000-0002-7990-754X
Eun Young KimDepartment of Biomedical Sciences, Ajou University Graduate School of Medicine, 164 Worldcup-ro, Suwon, Kyunggi-do, Republic of Korea. ekim@ajou.ac.kr.ORCID 0000-0001-6466-8622
Ajou University · KRGwangju Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolism influences locomotor behaviors, but the understanding of neural curcuit control for that is limited. Under standard light-dark cycles, Drosophila exhibits bimodal morning (M) and evening (E) locomotor activities that are controlled by clock neurons. Here, we showed that a high-nutrient diet progressively extended M activity but not E activity. Drosophila tachykinin (DTk) and Tachykinin-like receptor at 86C (TkR86C)-mediated signaling was required for the extension of M activity. DTk neurons were anatomically and functionally connected to the posterior dorsal neuron 1s (DN1

Indexed as

AnimalsCircadian RhythmDrosophilaDrosophila ProteinsFemaleLocomotionMalePhotoperiodProtein PrecursorsTachykininsDrosophila ProteinsProtein PrecursorsTachykininsTk protein, Drosophila

Identifiers

PMID34099879
PMCPMC8184744
OpenAlexW3168320748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.