ArticleScientific reports2021
Clinical significance of subclinical atherosclerosis in retinal vein occlusion.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Association of arterial stiffness and eye disease: a systematic review and meta-analysis.BMJ open ophthalmology · 2025Pooled it
- Plasma lipid levels and risk of retinal vascular occlusion: A genetic study using Mendelian randomization.Frontiers in endocrinology · 2022Pooled it
- Retinal findings in familial hypercholesterolemia: An exploratory case-control study.Atherosclerosis plus · 2026Article
- Risk of Adverse Systemic Events in Retinal Vein Occlusion.Ophthalmology. Retina · 2025Article
- Endothelial Glycocalyx Damage and Arterial Thickness in Patients with Retinal Vein Occlusion (RVO).Journal of clinical medicine · 2024Article
- Vitamin D deficiency in patients with retinal vein occlusion: a systematic review and meta-analysis.International journal of retina and vitreous · 2024Review
- Article
- Maximum carotid intima-media thickness and NT-pro BNP in association with retinal vein occlusion.PloS one · 2023Article
- Predicting CT-Based Coronary Artery Disease Using Vascular Biomarkers Derived from Fundus Photographs with a Graph Convolutional Neural Network.Diagnostics (Basel, Switzerland) · 2022Article
- Evaluation of Systemic Endothelial Dysfunction in Retinal Vein Occlusions.Beyoglu eye journal · 2022Article
- Alteration of plasma von Willebrand factor in the treatment of retinal vein occlusion with cystoid macular edema.PloS one · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Retinal vein occlusion (RVO) is associated with atherosclerotic cardiovascular risk factors; however, its association with the specific markers of subclinical atherosclerosis has not yet been established. To investigate this association, we compared 70 patients with RVO to 70 age- and sex-matched patients without RVO. Low-density lipoprotein cholesterol (LDL-C) levels and brachial-ankle pulse wave velocity (baPWV) were significantly higher in the RVO group than in the control group. Carotid plaques (54.3% vs. 28.6%, p = 0.004) were more frequent in the RVO group. Multivariate logistic regression analysis showed that the presence of carotid plaques (odds ratio [OR]: 3.15, 95% confidence interval [CI] 1.38-7.16, p = 0.006), as well as smoking, LDL-C level, and baPWV were associated with RVO. Additionally, a multinomial logistic regression model showed that the presence of carotid plaques (OR: 3.94, 95% CI 1.65-9.41, p = 0.002) and LDL-C level were associated with branch RVO, whereas smoking and baPWV were associated with central RVO. In conclusion, RVO was associated with subclinical atherosclerosis markers, including carotid plaques and baPWV. These results support the hypothesis that atherosclerosis contributes to the etiology of RVO and suggest the evaluation of subclinical atherosclerosis in patients with RVO.
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