Evidence map›Paper›PMID 34099762›Full record

ArticleScientific reports2021

Housing quality and behavior affect brain health and anxiety in healthy Japanese adults.

Juan Cesar D Pineda, Keisuke Kokubun, Toshiharu Ikaga, Yoshinori Yamakawa

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  10. Neurosustainability.Frontiers in human neuroscience · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Effect of Housing Quality on the Mental Health of University Students during the COVID-19 Lockdown.International journal of environmental research and public health · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juan Cesar D PinedaOpen Innovation Institute, Kyoto University, Kyoto, Japan. pineda.juancesar.4z@kyoto-u.ac.jp.
Keisuke KokubunOpen Innovation Institute, Kyoto University, Kyoto, Japan.
Toshiharu IkagaFaculty of Science and Technology, Keio University, Yokohama, Kanagawa, Japan.
Yoshinori YamakawaOpen Innovation Institute, Kyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Countless studies in animals have shown how housing environments and behaviors can significantly affect anxiety and brain health, giving valuable insight as to whether this is applicable in the human context. The relationship between housing, behavior, brain health, and mental wellbeing in humans remains poorly understood. We therefore explored the interaction of housing quality, weekend/holiday sedentary behavior, brain structure, and anxiety in healthy Japanese adults. Whole-brain structural magnetic resonance imaging (MRI) methods based on gray matter volume and fractional anisotropy were used as markers for brain health. Correlation tests were conducted, and then adjusted for multiple comparisons using the False Discovery Rate method. Housing quality and weekend/holiday sedentary behavior were associated with fractional anisotropy, but not with gray matter volume. Fractional anisotropy showed significant associations with anxiety. Lastly, both weekend/holiday sedentary behavior and housing quality were indirectly associated with anxiety through fractional anisotropy. These results add to the limited evidence surrounding the relationship among housing, behavior, and the brain. Furthermore, these results show that behavior and housing qualities can have an indirect impact on anxiety through neurobiological markers such as fractional anisotropy.

Indexed as

HousingAdultAgedAnisotropyAnxietyBehaviorFemaleGray MatterHumansJapanMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingNeuropsychological Tests

Identifiers

PMID34099762
PMCPMC8184752

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.