Evidence map›Paper›PMID 34099754›Full record

Observational studyScientific reports2021

Prospective cohort study on hospitalised patients with suspected urinary tract infection and risk factors por multidrug resistance.

Victor Garcia-Bustos, Ana Isabel Renau Escrig, Cristina Campo López, Rosario Alonso Estellés, Koen Jerusalem, Marta Dafne Cabañero-Navalón, Victoria Morell Massó, Ignacio-Antonio Sigona-Giangreco, José Miguel Sahuquillo-Arce, Iván Castro Hernández and 1 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 25 citations in OpenAlex.

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  17. Phage P2-71 against multi-drug resistantFrontiers in cellular and infection microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Victor Garcia-BustosDepartment of Internal Medicine, University and Polytechnic Hospital La Fe, Avinguda Fernando Abril Martorell, 106, 46026, Valencia, Spain. victorgarciabustos@gmail.com.
Ana Isabel Renau EscrigDepartment of Internal Medicine, University and Polytechnic Hospital La Fe, Avinguda Fernando Abril Martorell, 106, 46026, Valencia, Spain.
Cristina Campo LópezDepartment of Internal Medicine, University and Polytechnic Hospital La Fe, Avinguda Fernando Abril Martorell, 106, 46026, Valencia, Spain.
Rosario Alonso EstellésDepartment of Internal Medicine, University and Polytechnic Hospital La Fe, Avinguda Fernando Abril Martorell, 106, 46026, Valencia, Spain.
Koen JerusalemDepartment of Internal Medicine, Manises Hospital, Manises, Spain.
Marta Dafne Cabañero-NavalónDepartment of Internal Medicine, University and Polytechnic Hospital La Fe, Avinguda Fernando Abril Martorell, 106, 46026, Valencia, Spain.
Victoria Morell MassóDepartment of Internal Medicine, General Hospital La Mancha Centro, Alcázar de San Juan, Ciudad Real, Spain.
Ignacio-Antonio Sigona-GiangrecoDepartment of Microbiology, University and Polytechnic Hospital La Fe, Valencia, Spain.
José Miguel Sahuquillo-ArceDepartment of Microbiology, University and Polytechnic Hospital La Fe, Valencia, Spain.
Iván Castro HernándezDepartment of Internal Medicine, University and Polytechnic Hospital La Fe, Avinguda Fernando Abril Martorell, 106, 46026, Valencia, Spain.
Miguel Salavert LletíInfectious Disease Unit, University and Polytechnic Hospital La Fe, Valencia, Spain.
Hospital Universitari i Politècnic La Fe · ESHospital de Manises · ESHospital General Universitario de Ciudad Real · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary tract infections (UTIs) are among the most common bacterial infections and a frequent cause for hospitalization in the elderly. The aim of our study was to analyse epidemiological, microbiological, therapeutic, and prognostic of elderly hospitalised patients with and to determine independent risk factors for multidrug resistance and its outcome implications. A single-centre observational prospective cohort analysis of 163 adult patients hospitalized for suspected symptomatic UTI in the Departments of Internal Medicine, Infectious Diseases and Short-Stay Medical Unit of a tertiary hospital was conducted. Most patients currently admitted to hospital for UTI are elderly and usually present high comorbidity and severe dependence. More than 55% met sepsis criteria but presented with atypical symptoms. Usual risk factors for multidrug resistant pathogens were frequent. Almost one out of five patients had been hospitalized in the 90 days prior to the current admission and over 40% of patients had been treated with antibiotic in the previous 90 days. Infection by MDR bacteria was independently associated with the previous stay in nursing homes or long-term care facilities (LTCF) (OR 5.8, 95% CI 1.17-29.00), permanent bladder catheter (OR 3.55, 95% CI 1.00-12.50) and urinary incontinence (OR 2.63, 95% CI 1.04-6.68). The degree of dependence and comorbidity, female sex, obesity, and bacteraemia were independent predictors of longer hospital stay. The epidemiology and presentation of UTIs requiring hospitalisation is changing over time. Attention should be paid to improve management of urinary incontinence, judicious catheterisation, and antibiotic therapy.

Indexed as

AdultAgedAged, 80 and overAnti-Bacterial AgentsCardiovascular DiseasesDrug Resistance, Multiple, BacterialFemaleHospitalizationHumansLength of StayLinear ModelsLiver DiseasesMaleMiddle AgedOutcome Assessment, Health CareProspective StudiesAnti-Bacterial Agents

Identifiers

PMID34099754
PMCPMC8184807
OpenAlexW3170706333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.