Evidence map›Paper›PMID 34099572›Full record

ArticleTobacco control2023

Trends in e-cigarette brands, devices and the nicotine profile of products used by youth in England, Canada and the USA: 2017-2019.

David Hammond, Jessica L Reid, Robin Burkhalter, Richard J O'Connor, Maciej L Goniewicz, Olivia A Wackowski, James F Thrasher, Sara C Hitchman

Abstract read
In one paragraph

Article in Tobacco control, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  2. Recommendations on interventions for tobacco smoking cessation in adults in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  3. Comparing brain absorption and lung deposition of nicotine salts and free-base e-cigarettes: insights from [Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Article
  6. What is the Addictive Potential from Vaping?Nordisk alkohol- & narkotikatidskrift : NAT · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Targeting GPR3 as a novel approach for nicotine cessation therapeutic development.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Preventive medicine reports · 2025
    Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Decoding Vaping: Empowering Youth Through Media Literacy Based E-cigarette Educational Program.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David HammondSchool of Public Health & Health Systems, University of Waterloo, Waterloo, Ontario, Canada dhammond@uwaterloo.ca.
Jessica L ReidSchool of Public Health & Health Systems, University of Waterloo, Waterloo, Ontario, Canada.ORCID 0000-0001-9909-6265
Robin BurkhalterSchool of Public Health & Health Systems, University of Waterloo, Waterloo, Ontario, Canada.
Richard J O'ConnorRoswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Maciej L GoniewiczRoswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID 0000-0001-6748-3068
Olivia A WackowskiSchool of Public Health, Rutgers, The State University of New Jersey, Piscataway Township, NJ, USA.ORCID 0000-0001-9159-5473
James F ThrasherArnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Sara C HitchmanInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0001-6155-6916

Funding

Vaporized Nicotine Product Initiation Among Youth in the US, Canada, and England: Methods to Predict Uptake and Policy EfficacyP01CA200512 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FONG, GEOFFREY T · 2016 to 2025
$25.3M
CIHRNCI NIH HHS P01 CA200512
6 · The paper itself

Abstract

backgroundThe e-cigarette market has rapidly evolved, with a shift towards higher nicotine concentration and salt-based products, such as

methodsRepeat cross-sectional online surveys were conducted in 2017, 2018 and 2019, with national samples of youth aged 16-19 years recruited from commercial panels in Canada (n=12 018), England (n=11 362) and the USA (n=12 110). Regression models examined differences between countries and over time in the types of e-cigarette products used (design and nicotine content), reasons for using brands and differences in patterns of use, sociodemographics and dependence symptoms by brand/nicotine content.

resultsIn 2019, the use of pod- or cartridge-style e-cigarettes was greater in Canada and the USA than England, with

conclusionsThe use of high-nicotine salt-based products is associated with greater symptoms of dependence, including

Indexed as

Electronic Nicotine Delivery SystemsTobacco ProductsVapingAdolescentCanadaCross-Sectional StudiesHumansNicotineNicotineelectronic nicotine delivery devicesnicotinepriority/special populations

Identifiers

PMID34099572
PMCPMC9359003

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.