Evidence map›Paper›PMID 34099272›Full record

ArticleThe Journal of thoracic and cardiovascular surgery2022

Interhospital variability in health care-associated infections and payments after durable ventricular assist device implant among Medicare beneficiaries.

Donald S Likosky, Guangyu Yang, Min Zhang, Preeti N Malani, Michael D Fetters, Raymond J Strobel, Carol E Chenoweth, Hechuan Hou, Francis D Pagani, Michigan Congestive Heart Failure Investigators

Open access · hybridAbstract read
In one paragraph

Article in The Journal of thoracic and cardiovascular surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Interhospital variability in 180-day infections following cardiac surgery.The Journal of thoracic and cardiovascular surgery · 2025
    Article
  4. Article
  5. Article
  6. Infections following left ventricular assist device implantation and 1-year health-related quality of life.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  7. Article
  8. Article
  9. Incompleteness of health-related quality of life assessments before left ventricular assist device implant: A novel quality metric.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2022
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Donald S LikoskyDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Mich. Electronic address: likosky@med.umich.edu.
Guangyu YangDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Mich.
Min ZhangDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Mich.
Preeti N MalaniDivision of Infectious Diseases, Department of Medicine, Michigan Medicine, University of Michigan, Ann Arbor, Mich.
Michael D FettersDepartment of Family Medicine, Michigan Medicine, University of Michigan, Ann Arbor, Mich.
Raymond J StrobelDepartment of Surgery, University of Virginia, Charlottesville, Va.
Carol E ChenowethDivision of Infectious Diseases, Department of Medicine, Michigan Medicine, University of Michigan, Ann Arbor, Mich.
Hechuan HouDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Mich.
Francis D PaganiDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Mich.
Michigan Congestive Heart Failure Investigators
Michigan Medicine · USUniversity of Michigan–Ann Arbor · USUniversity of Virginia · US

Funding

TRAINING IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007853 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David J. Pinsky · 1996 to 2026
$11.6M
Novel Assessments of Technical and Non-Technical Cardiac Surgery QualityR01HL146619 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIKOSKY, DONALD S, PAGANI, FRANCIS D · 2020 to 2024
$3.4M
Understanding and Addressing Variation in Healthcare-Associated Infections After Durable Ventricular Assist Device TherapyR01HS026003 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIKOSKY, DONALD S · 2018 to 2022
$2.3M
AHRQ HHS R01 HS026003NHLBI NIH HHS HHSN268201100025CNHLBI NIH HHS R01 HL146619NHLBI NIH HHS T32 HL007853
6 · The paper itself

Abstract

objectiveThe objective of this study was to investigate variations across hospitals in infection rates and associated costs, the latter reflected in 90-day Medicare payments. Despite high rates and expenditures of health care--associated infections associated with durable ventricular assist device implantation, few studies have examined interhospital variation and associated costs.

methodsClinical data on 8688 patients who received primary durable ventricular assist devices from July 2008 to July 2017 from the Society of Thoracic Surgeons Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) hospitals (n = 120) were merged with postimplantation 90-day Medicare claims. Terciles of hospital-specific, risk-adjusted infection rates per 100 patient-months were estimated using Intermacs and associated with Medicare payments (among 5440 Medicare beneficiaries). Primary outcomes included infections within 90 days of implantation and Medicare payments.

resultsThere were 3982 infections identified among 27.8% (2417/8688) of patients developing an infection. The median (25th, 75th percentile) adjusted incidence of infections (per 100 patient-months) across hospitals was 14.3 (9.3, 19.5) and varied according to hospital (range, 0.0-35.6). Total Medicare payments from implantation to 90 days were 9.0% (absolute difference: $13,652) greater in high versus low infection tercile hospitals (P < .0001). The period between implantation to discharge accounted for 73.1% of the difference in payments during the implantation to 90-day period across terciles.

conclusionsHealth care--associated infection rates post durable ventricular assist device implantation varied according to hospital and were associated with increased 90-day Medicare expenditures. Interventions targeting preventing infections could improve the value of durable ventricular assist device support from the societal and hospital perspectives.

Indexed as

Cross InfectionHeart-Assist DevicesHeart FailureAgedHealth ExpendituresHumansMedicarePatient DischargeRegistriesRetrospective StudiesTreatment OutcomeUnited Statesexpenditureinfectionventricular assist device

Identifiers

PMID34099272
PMCPMC10150658
OpenAlexW3158571712

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.