Evidence map›Paper›PMID 34099035›Full record

ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2021

HealthSWEDE: costs with sublingual immunotherapy-a Swedish questionnaire study.

Petter Olsson, Carl Skröder, Lars Ahlbeck, Frida Hjalte, Karl-Olof Welin, Ulla Westin, Morgan Andersson, Cecilia Ahlström-Emanuelsson, Lars-Olaf Cardell

Open access · goldAbstract read
In one paragraph

Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Intralymphatic immunotherapy with birch and grass pollen extracts. A randomized double-blind placebo-controlled clinical trial.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2023
    Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Petter OlssonDivision of Ear, Nose and Throat Diseases, Department of Clinical Sciences, Intervention and Technology, Klinisk Vetenskap (CLINTEC), Karolinska Institutet, Intervention och teknik, H9 Öron-, näs, och halssjukdomar, 171 77, Stockholm, Sweden. petter.olsson@ki.se.ORCID http://orcid.org/0000-0002-3913-3914
Carl SkröderDepartment of Otorhinolaryngology, Head and Neck Surgery, Institute of Clinical Sciences, Skåne University Hospital, Lund, Sweden.
Lars AhlbeckAllergy Center, Linköping University Hospital, Linköping, Sweden.
Frida HjalteThe Swedish Institute for Health Economics (IHE), Lund, Sweden.
Karl-Olof WelinThe Swedish Institute for Health Economics (IHE), Lund, Sweden.
Ulla WestinDepartment of Otorhinolaryngology, Head and Neck Surgery, Institute of Clinical Sciences, Skåne University Hospital, Lund, Sweden.
Morgan AnderssonDepartment of Otorhinolaryngology, Head and Neck Surgery, Institute of Clinical Sciences, Skåne University Hospital, Lund, Sweden.
Cecilia Ahlström-EmanuelssonDepartment of Otorhinolaryngology, Head and Neck Surgery, Institute of Clinical Sciences, Skåne University Hospital, Lund, Sweden.
Lars-Olaf CardellDivision of Ear, Nose and Throat Diseases, Department of Clinical Sciences, Intervention and Technology, Klinisk Vetenskap (CLINTEC), Karolinska Institutet, Intervention och teknik, H9 Öron-, näs, och halssjukdomar, 171 77, Stockholm, Sweden.
Skåne University Hospital · SEKarolinska Institutet · SESwedish Institute for Health Economics · SELinköping University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this cross-sectional survey was to compare the health-economic consequences for allergic rhinitis (AR) patients treated with sublingual Immunotherapy (SLIT) in terms of direct and indirect costs with a reference population of patients receiving standard of care pharmacological therapy.

methodsPrimary objective was to analyse the health-economic consequences of SLIT for grass pollen allergy in Sweden vs reference group waiting for subcutaneous immunotherapy (SCIT). A questionnaire was mailed to two groups of AR patients.

resultsThe questionnaire was distributed to 548 patients, 307 with SLIT and 241 in reference group (waiting for SCIT). Response rate was 53.8%. Mean annual costs were higher for reference patients than SLIT group; € 3907 (SD 4268) vs € 2084 (SD 1623) p < 0.001. Mean annual direct cost was higher for SLIT-patients, € 1191 (SD 465) than for reference, € 751 (SD 589) p < 0.001. Mean annual indirect costs for combined absenteeism and presenteeism were lower for patients treated with SLIT, € 912 (SD 1530), than for reference, € 3346 (SD 4120) p < 0.001, with presenteeism as main driver.

conclusionsSLIT seems to be a cost-beneficial way to treat seasonal AR. This information might be used to guide future recommendations.

Indexed as

AbsenteeismAllergic rhinitisDirect costsIndirect costsPresenteeism

Identifiers

PMID34099035
PMCPMC8183062
OpenAlexW3167683881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.