Evidence map›Paper›PMID 34099003›Full record

Observational studyJournal of cardiothoracic surgery2021

Re-exploration for bleeding after cardiac surgery: revaluation of urgency and factors promoting low rate.

Ahmed Abdelrahman Elassal, Khalid Ebrahim Al-Ebrahim, Ragab Shehata Debis, Ehab Sobhy Ragab, Mazen Shamsaldeen Faden, Mazin Adel Fatani, Amr Ragab Allam, Ahmed Hasan Abdulla, Auhood Mohammednoor Bukhary, Nada Ahmed Noaman and 1 more

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06511778 (sTErnAl heMostasiS Trial), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06511778 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

sTErnAl heMostasiS Trial (TEAMS Trial)

TypeinterventionalSponsorWakeMed Health and HospitalsRan2024 to 2026Enrolled60ConditionsExcessive Bleeding During SurgeryArmsHemoblast Bellows application
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ahmed Abdelrahman ElassalDepartment of Surgery, Cardiac Surgery Unit, King Abdulaziz University, Jeddah, 21589, Saudi Arabia. samalassal1434@gmail.com.ORCID http://orcid.org/0000-0002-2497-6978
Khalid Ebrahim Al-EbrahimDepartment of Surgery, Cardiac Surgery Unit, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Ragab Shehata DebisDepartment of Surgery, Cardiac Surgery Unit, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Ehab Sobhy RagabCardiothoracic Surgery Department, Zagazig University, Zagazig, Egypt.
Mazen Shamsaldeen FadenDepartment of Anesthesia and Critical Care, King Abdulaziz University, Jeddah, Saudi Arabia.
Mazin Adel FataniDepartment of Surgery, Umm Al-Qura University, Makkah, Saudi Arabia.
Amr Ragab AllamDepartment of Surgery, Cardiac Surgery Unit, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Ahmed Hasan AbdullaDepartment of Surgery, Cardiac Surgery Unit, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Auhood Mohammednoor BukharyDepartment of Anesthesia and Critical Care, King Abdulaziz University, Jeddah, Saudi Arabia.
Nada Ahmed NoamanDepartment of Anesthesia and Critical Care, King Abdulaziz University, Jeddah, Saudi Arabia.
Osama Saber EldibCardiothoracic Surgery Department, Zagazig University, Zagazig, Egypt.
King Abdulaziz University · SAZagazig University · EGUmm al-Qura University · SA

Funding

King Abdulaziz University DF- 729 - 140 - 1441
6 · The paper itself

Abstract

backgroundRe-exploration of bleeding after cardiac surgery is associated with significant morbidity and mortality. Perioperative blood loss and rate of re-exploration are variable among centers and surgeons.

objectiveTo present our experience of low rate of re-exploration based on adopting checklist for hemostasis and algorithm for management.

methodsRetrospective analysis of medical records was conducted for 565 adult patients who underwent surgical treatment of congenital and acquired heart disease and were complicated by postoperative bleeding from Feb 2006 to May 2019. Demographics of patients, operative characteristics, perioperative risk factors, blood loss, requirements of blood transfusion, morbidity and mortality were recorded. Logistic regression was used to identify predictors of re-exploration and determinants of adverse outcome.

resultsThirteen patients (1.14%) were reexplored for bleeding. An identifiable source of bleeding was found in 11 (84.6%) patients. Risk factors for re-exploration were high body mass index, high Euro SCORE, operative priority (urgent/emergent), elevated serum creatinine and low platelets count. Re-exploration was significantly associated with increased requirements of blood transfusion, adverse effects on cardiorespiratory state (low ejection fraction, increased s. lactate, and prolonged period of mechanical ventilation), longer intensive care unit stay, hospital stay, increased incidence of SWI, and higher mortality (15.4% versus 2.53% for non-reexplored patients). We managed 285 patients with severe or massive bleeding conservatively by hemostatic agents according to our protocol with no added risk of morbidity or mortality.

conclusionLow rate of re-exploration for bleeding can be achieved by strict preoperative preparation, intraoperative checklist for hemostasis implemented by senior surgeons and adopting an algorithm for management.

Indexed as

AlgorithmsCardiac Surgical ProceduresChecklistAdultAgedFemaleFollow-Up StudiesHemostasis, SurgicalHumansIncidenceLogistic ModelsMaleMiddle AgedPerioperative CarePostoperative HemorrhageReoperationBleedingCardiac surgeryRe-exploration

Identifiers

PMID34099003
PMCPMC8183590
OpenAlexW3167973459

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.