Observational studyJournal of cardiothoracic surgery2021
Re-exploration for bleeding after cardiac surgery: revaluation of urgency and factors promoting low rate.
Observational study in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06511778 (sTErnAl heMostasiS Trial), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
sTErnAl heMostasiS Trial (TEAMS Trial)
Who cites it
20 citing papers in PubMed, 50 citations in OpenAlex.
- Effect of a water-soluble alkylene oxide copolymer based bone hemostat in cardiac surgery: a prospective, multicenter, single-arm study.Journal of cardiothoracic surgery · 2026Article
- Multi-Output Machine Learning for Prediction of Postoperative Outcomes After Cardiac Surgery Using Patient Blood Management Biomarkers.Journal of clinical medicine · 2026Article
- Article
- Effects of Continuous Postoperative Pericardial FLUshing with Investigational Device on Postoperative Re-Explorations for Bleeding (FLUID)-Randomized Clinical Trial.Journal of clinical medicine · 2026Article
- Impact of surgical urgency on outcomes after minimally invasive coronary artery bypass surgery: a retrospective cohort study.Journal of cardiothoracic surgery · 2025Article
- Impact of surgical re-exploration on 30-day mortality for post-operative bleeding in off-pump coronary artery bypass grafting.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Article
- Factors Associated With Postoperative Complications Among Critical Patients Undergoing Open-Heart Surgery: A Cross-Sectional Study.Nursing open · 2025Article
- Direct-acting oral anticoagulant removal by intraoperative hemoadsorption in CABG and/or single valve surgery: interim analysis of the International Safe and Timely Antithrombotic Removal (STAR) registry.Journal of cardiothoracic surgery · 2025Observational
- Quality of registration and adherence to guidelines for blood management in CABG surgeries: a case study.Journal of cardiothoracic surgery · 2025Article
- Comprehensive Coagulation Management in Cardiac Surgery: Anticoagulants, Heparin Resistance, Monitoring, and Bleeding Risks : Coagulation Management in Cardiac Surgery.Galen medical journal · 2025Review
- Review
- Article
- Radical mediastinal lipectomy for tamponade-like cardiac physiology.Journal of cardiothoracic surgery · 2023Article
- Cardiac Surgery Morbidity and Mortality in Hypertensive and Arrhythmic Patients: A Retrospective Analysis.Cureus · 2023Article
- The Quality of Life in Patients With Valve Prosthesis After Undergoing Surgery for Valvular Heart Diseases.Cureus · 2023Article
- Early Re-Exploration versus Conservative Management for Postoperative Bleeding in Stable Patients after Coronary Artery Bypass Grafting: A Propensity Matched Study.Journal of clinical medicine · 2023Article
- Effect of Gender on Postoperative Outcome and Duration of Ventilation After Coronary Artery Bypass Grafting (CABG).Cureus · 2023Article
- Biomaterials as Haemostatic Agents in Cardiovascular Surgery: Review of Current Situation and Future Trends.Polymers · 2022Review
- Coronary Artery Bypass Grafting among Patients Undergoing Cardiac Surgery in a Tertiary Care Hospital: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundRe-exploration of bleeding after cardiac surgery is associated with significant morbidity and mortality. Perioperative blood loss and rate of re-exploration are variable among centers and surgeons.
objectiveTo present our experience of low rate of re-exploration based on adopting checklist for hemostasis and algorithm for management.
methodsRetrospective analysis of medical records was conducted for 565 adult patients who underwent surgical treatment of congenital and acquired heart disease and were complicated by postoperative bleeding from Feb 2006 to May 2019. Demographics of patients, operative characteristics, perioperative risk factors, blood loss, requirements of blood transfusion, morbidity and mortality were recorded. Logistic regression was used to identify predictors of re-exploration and determinants of adverse outcome.
resultsThirteen patients (1.14%) were reexplored for bleeding. An identifiable source of bleeding was found in 11 (84.6%) patients. Risk factors for re-exploration were high body mass index, high Euro SCORE, operative priority (urgent/emergent), elevated serum creatinine and low platelets count. Re-exploration was significantly associated with increased requirements of blood transfusion, adverse effects on cardiorespiratory state (low ejection fraction, increased s. lactate, and prolonged period of mechanical ventilation), longer intensive care unit stay, hospital stay, increased incidence of SWI, and higher mortality (15.4% versus 2.53% for non-reexplored patients). We managed 285 patients with severe or massive bleeding conservatively by hemostatic agents according to our protocol with no added risk of morbidity or mortality.
conclusionLow rate of re-exploration for bleeding can be achieved by strict preoperative preparation, intraoperative checklist for hemostasis implemented by senior surgeons and adopting an algorithm for management.
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