ArticleMicrobial cell factories2021
Site-directed mutagenesis of the quorum-sensing transcriptional regulator SinR affects the biosynthesis of menaquinone in Bacillus subtilis.
Article in Microbial cell factories, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- Metabolic engineering of Escherichia coli BW25113 for the production of Vitamin KJournal of biological engineering · 2026Article
- Metabolic Engineering Strategy forFoods (Basel, Switzerland) · 2025Review
- Repurposing the bacterial surface display technology for drug delivery.Advanced drug delivery reviews · 2025Review
- Enhancement of menaquinone- 7 production through immobilization with hydrogel-based porous membranes.Applied microbiology and biotechnology · 2025Article
- Engineering a PhrC-RapC-SinR quorum sensing molecular switch for dynamic fine-tuning of menaquinone-7 synthesis in Bacillus subtilis.Microbial cell factories · 2025Article
- Natural pigments derived from plants and microorganisms: classification, biosynthesis, and applications.Plant biotechnology journal · 2025Review
- Combination of SPH and SP80 prolongs the lifespan ofFrontiers in microbiology · 2025Article
- Adaptive laboratory evolution for improved tolerance of vitamin K in Bacillus subtilis.Applied microbiology and biotechnology · 2024Article
- Enhancing menaquinone-7 biosynthesis through strengthening precursor supply and product secretion.Bioprocess and biosystems engineering · 2024Article
- Brij-58 supplementation enhances menaquinone-7 biosynthesis and secretion in Bacillus natto.Applied microbiology and biotechnology · 2023Article
- Enhanced vitamin K2 production by engineered Bacillus subtilis during leakage fermentation.World journal of microbiology & biotechnology · 2023Article
- Characterization of a Riboflavin-Producing Mutant ofMicroorganisms · 2023Article
- Probiotic properties ofFrontiers in microbiology · 2023Article
- Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis.Microbial cell factories · 2022Article
- Effects of Alkali Stress on the Growth and Menaquinone-7 Metabolism ofFrontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMenaquinone (MK-7) is a highly valuable vitamin K
resultsIn this study, the QS transcriptional regulator SinR, which plays a significant role in biofilm formation and MK production simultaneously, was selected, and its site-directed mutants were constructed. Among these mutants, sinR knock out strain (KO-SinR) increased the biofilm biomass by 2.8-fold compared to the wild-type. SinR
conclusionsIn this study, we report for the first time that SinR
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