Evidence map›Paper›PMID 34098826›Full record

ReviewExpert opinion on therapeutic targets2021

Peripheral vascular disease: preclinical models and emerging therapeutic targeting of the vascular endothelial growth factor ligand-receptor system.

Vijay Chaitanya Ganta, Brian H Annex

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on therapeutic targets, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Endothelial CEPT1 Promotes Angiogenesis Through PPARα and VEGF-A Signaling.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. CD34Science advances · 2023
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vijay Chaitanya GantaDepartment of Medicine and Vascular Biology Center, Augusta University, Augusta, GA, USA.
Brian H AnnexDepartment of Medicine and Vascular Biology Center, Augusta University, Augusta, GA, USA.
Augusta University · US

Funding

Systems Biology of Angiogenesis in Peripheral Arterial DiseaseR01HL101200 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI POPEL, ALEKSANDER S. · 2010 to 2022
$10.7M
Clinical Phenotyping and Disease Specific Sampling to Identify Non-coding RNAs for Human Therapeutics in PADR01HL150003 · NHLBI · AUGUSTA UNIVERSITY · PI ANNEX, BRIAN H, MCCLUNG, JOSEPH MATTHEW · 2020 to 2023
$3.0M
Precision Medicine for Therapeutic Angiogenesis in Peripheral Arterial Disease: Targeting of the IL21R PathwayR01HL148590 · NHLBI · AUGUSTA UNIVERSITY · PI ANNEX, BRIAN H · 2019 to 2022
$2.9M
The Anti-angiogenic VEGF165b and VEGFR1 Signaling in Peripheral Artery DiseaseR01HL141325 · NHLBI · UNIVERSITY OF VIRGINIA · PI ANNEX, BRIAN H · 2019 to 2022
$2.7M
New Roles for VEGFR1 in AngiogenesisR01GM129074 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI MAC GABHANN, FEILIM C · 2018 to 2021
$2.6M
A Two Amino Acid Switch in the Anti-angiogenic VEGF165b isoform creates a Novel Agent for Therapeutic Angiogenesis in Peripheral Artery DiseaseR01HL146673 · NHLBI · UNIVERSITY OF VIRGINIA · PI GANTA, VIJAY CHAITANYA · 2019 to 2023
$1.9M
NHLBI NIH HHS R01 HL101200NHLBI NIH HHS R01 HL141325NHLBI NIH HHS R01 HL146673NHLBI NIH HHS R01 HL148590NHLBI NIH HHS R01 HL150003NIGMS NIH HHS R01 GM129074
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Molecular Targeted TherapyAlternative SplicingAngiogenesis InhibitorsAnimalsHumansLigandsNeovascularization, PathologicPeripheral Arterial DiseaseProtein IsoformsSignal TransductionVascular Endothelial Growth Factor AAngiogenesis InhibitorsLigandsProtein IsoformsVascular Endothelial Growth Factor AVEGFA protein, humanalternate splicingangiogenesisatherosclerotic occlusionchronic limb ischemiachronic limb-threatening ischemiaEndotheliumischemiamacrophage polarizationperipheral artery disease

Identifiers

PMID34098826
PMCPMC8573823
OpenAlexW3172446261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.