Evidence map›Paper›PMID 34098303›Full record

ArticleJournal of substance abuse treatment2021

Changes in methadone program practices and fatal methadone overdose rates in Connecticut during COVID-19.

Sarah Brothers, Adam Viera, Robert Heimer

Open access · bronzeAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 3 pooled it
16.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
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  3. Have Deaths of Despair Risen during the COVID-19 Pandemic? A Systematic Review.International journal of environmental research and public health · 2022
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  8. Developing and validating measures of take-home methadone with administrative data.Journal of substance use and addiction treatment · 2026
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  9. Insurance coverage and provision of opioid disorder treatment: Evidence from Medicare.Journal of policy analysis and management : [the journal of the Association for Public Policy Analysis and Management] · 2026
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sarah BrothersDepartment of Sociology, Yale University, New Haven, CT 06520-8265, United States of America. Electronic address: Sarah.brothers@yale.edu.
Adam VieraDepartment of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT 06510-8034, United States of America.
Robert HeimerDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510-8034, United States of America.
Yale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to the COVID-19 pandemic, the Substance Abuse and Mental Health Services Administration (SAMHSA) has relaxed restrictions on methadone treatment in the United States. There is concern that the relaxation may increase fatal overdose rates. This study examines opioid treatment program (OTP) changes to methadone treatment during COVID-19 and changes in fatal methadone-involved overdose rates in Connecticut.

methodsFrom July 8th to August 18th, 2020, we conducted a comprehensive state-wide survey of all eight OTPs that dispense methadone in Connecticut to examine programmatic changes during COVID-19. We also analyzed state-level data on confirmed accidental opioid-involved deaths to assess if relaxation of take-home dosing restrictions and in-person attendance requirements correlated with increased methadone-involved fatal overdose rates.

resultsOTPs reported implementing multiple changes to methadone treatment in response to the COVID-19 pandemic. The percent of patients receiving 28-day take-home doses increased from 0.1% to 16.8%, 14-day take-home doses increased from 14.2% to 26.8%, and the percent receiving one or no take-home doses decreased from 37.5% to 9.6%. Monthly or more frequent drug testing decreased from 15% to 4.6% and 75.2% of individual counseling for methadone patients transitioned to telehealth. However, changes to methadone treatment varied considerably by program. OTP providers said restrictions on methadone should be relaxed and increases in take-home dosing as well as telehealth should be continued in non-pandemic situations. Methadone-involved fatalities relative to other opioid-involved fatalities did not increase in Connecticut following changes in OTP practices.

conclusionsConnecticut OTPs relaxed methadone treatment requirements during COVID-19. Since relaxing restrictions on methadone treatment has not increased fatal overdoses, we recommend that the reductions in-person dosing and attendance requirements implemented during the COVID-19 pandemic should be continued and made permanent.

Indexed as

COVID-19Drug OverdoseOpioid-Related DisordersAnalgesics, OpioidConnecticutHumansMethadoneOpiate Substitution TreatmentPandemicsSARS-CoV-2United StatesAnalgesics, OpioidMethadoneCOVID-19Medication-based treatmentMethadoneOpioid use disorderOverdoseTelehealth

Identifiers

PMID34098303
PMCPMC9758251
OpenAlexW3158184655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.