Evidence map›Paper›PMID 34098203›Full record

ArticleJournal of substance abuse treatment2022

Evaluating buprenorphine prescribing and opioid-related health outcomes following the expansion the buprenorphine waiver program.

Christopher L Rowe, Jennifer Ahern, Alan Hubbard, Phillip O Coffin

Abstract read
In one paragraph

Article in Journal of substance abuse treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christopher L RoweDivision of Epidemiology, School of Public Health, University of California, Berkeley, 2121 Berkeley Way, Floor 5, Berkeley, CA 94704, USA; Center on Substance Use and Health, San Francisco Department of Public Health, 25 Van Ness, Suite 500, San Francisco, CA 94102, USA. Electronic address: chrisrowe@berkeley.edu.
Jennifer AhernDivision of Epidemiology, School of Public Health, University of California, Berkeley, 2121 Berkeley Way, Floor 5, Berkeley, CA 94704, USA.
Alan HubbardDivision of Biostatistics, School of Public Health, University of California, Berkeley, 2121 Berkeley Way, Floor 5, Berkeley, CA 94704, USA.
Phillip O CoffinCenter on Substance Use and Health, San Francisco Department of Public Health, 25 Van Ness, Suite 500, San Francisco, CA 94102, USA; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California, San Francisco, 533 Parnassus Ave, San Francisco, CA 94143, USA.

Funding

Midcareer K24 Award for Mentoring and Patient-Oriented ResearchK24DA042720 · NIDA · SAN FRANCISCO DEPARTMENT OF PUBLIC HEALTH · PI PHILLIP O COFFIN · 2016 to 2026
$1.6M
Evaluating the effects of two federal policies on buprenorphine prescribing andopioid-related health outcomesF31DA047770 · NIDA · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROWE, CHRISTOPHER · 2019 to 2020
$74k
NIDA NIH HHS F31 DA047770NIDA NIH HHS K24 DA042720
6 · The paper itself

Abstract

aimsTo evaluate associations between new types of buprenorphine waivers (nurse practitioner and physician assistant [NP/PA]; 275-patient limit [MD/DO-275]) and both buprenorphine prescribing and health outcomes.

methodsUsing comprehensive county-level data from California 2010-2018, we modeled quarterly associations between numbers of NP/PA and MD/DO-275 waivers and rates of buprenorphine prescribing, opioid-related deaths, emergency department (ED) visits, and hospitalizations among all counties and separately among metropolitan and nonmetropolitan counties using Poisson regression models with county and quarter fixed effects and adjusting for time-varying covariates.

resultsEach additional NP/PA and MD/DO-275 waiver was associated with a 2.6% (95%CI: 1.1-4.1%) and 5.8% (4.1-7.4%) increase in buprenorphine prescribing among nonmetropolitan counties, respectively. Each additional MD/DO-275 waiver was associated with a 2.8% (1.0%-4.6%) increase in buprenorphine among metropolitan counties. There were no statistically significant associations between NP/PA waivers and buprenorphine prescribing among metropolitan counties or among either waiver type and opioid-related health outcomes.

conclusionsNP/PA waivers were associated with increased buprenorphine prescribing among nonmetropolitan counties and MD/DO-275 waivers were associated with increased buprenorphine prescribing among both metropolitan and nonmetropolitan counties.

Indexed as

BuprenorphineOpioid-Related DisordersAnalgesics, OpioidHumansOpiate Substitution TreatmentOutcome Assessment, Health CareUnited StatesAnalgesics, OpioidBuprenorphineBuprenorphineBuprenorphine waiver programOpioid agonist treatmentOpioid use disorder

Identifiers

PMID34098203
PMCPMC10023135

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.