Evidence map›Paper›PMID 34098014›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2022

Attention-Deficit/Hyperactivity Disorder Symptoms and Externalizing Progression in the LAMS Study: A Test of Trait Impulsivity Theory.

Ziv E Bell, Mary A Fristad, Eric A Youngstrom, L Eugene Arnold, Theodore P Beauchaine, LAMS Consortium

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Impulsivity as key bridge symptoms in cross-sectional and longitudinal networks of ADHD and ODD.Journal of child psychology and psychiatry, and allied disciplines · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ziv E BellThe Ohio State University, Columbus.
Mary A FristadNationwide Children's Hospital, Columbus, Ohio.
Eric A YoungstromUniversity of North Carolina Chapel Hill.
L Eugene ArnoldThe Ohio State University, Columbus; Nisonger Center for Excellence in Disabilities, Morgantown, West Virginia.
Theodore P BeauchaineThe Ohio State University, Columbus; Nisonger Center for Excellence in Disabilities, Morgantown, West Virginia. Electronic address: beauchaine.1@osu.edu.
LAMS Consortium
The Ohio State University · USNationwide Children's Hospital · USUniversity of North Carolina at Chapel Hill · USWest Virginia University · US

Funding

The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUL1TR002733 · NCATS · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2018 to 2022
$28.9M
Longitudinal Assessment of Manic SymptomsR01MH073967 · NIMH · JOHNS HOPKINS UNIVERSITY · PI FINDLING, ROBERT L · 2005 to 2016
$11.4M
Longitudinal Assessment of Manic Symptoms (LAMS)R01MH073953 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS, PHILLIPS, MARY LOUISE · 2005 to 2016
$8.7M
Longitudinal Assessment of Manic Symptoms (LAMS)R01MH073816 · NIMH · CINCINNATI CHILDRENS HOSP MED CTR · PI HOLLAND, SCOTT K. · 2005 to 2016
$5.9M
Longitudinal Assessment of Manic Symptoms (LAMS) StudyR01MH073801 · NIMH · OHIO STATE UNIVERSITY · PI FRISTAD, MARY A · 2005 to 2016
$5.9M
Targeting Corrosive Couple Conflict and Parent-Child Coercion to Impact Health Behaviors and Regimen AdherenceUH2DE025980 · NIDCR · NEW YORK UNIVERSITY · PI BEAUCHAINE, THEODORE PATRICK, HEYMAN, RICHARD ELIOT · 2015 to 2017
$1.8M
NCATS NIH HHS UL1 TR002733NIDCR NIH HHS UH2 DE025980NIMH NIH HHS R01 MH073801NIMH NIH HHS R01 MH073816NIMH NIH HHS R01 MH073953NIMH NIH HHS R01 MH073967
6 · The paper itself

Abstract

objectiveTo test differential prospective prediction of growth in externalizing behavior, including oppositional defiant disorder, conduct disorder, and substance use disorders, by earlier hyperactive-impulsive (HI) vs inattentive (IN) symptoms of attention-deficit/hyperactivity disorder (ADHD).

methodParticipants in the Longitudinal Assessment of Manic Symptoms (LAMS) Study (N = 685 at study entry), including 458 boys and 227 girls ages 6-12, completed full parent report and self-report assessments every year for 8 years on the Schedule for Affective Disorders and Schizophrenia for School-Age Children. Three sets of analyses were conducted. First, hierarchal regression (block entry) was used to test independent associations between HI symptoms and later externalizing outcomes, controlling for IN symptoms, and IN symptoms and later externalizing outcomes, controlling for HI symptoms. Second, logistic regression was used to test progression of DSM externalizing disorders. Third, tests of mediation were used to assess potentiation of externalizing progression through environmental risk mediators (eg, family environment, neighborhood violence).

resultsConsistent with hypotheses derived from trait impulsivity theories of externalizing behavior, HI symptoms of ADHD were associated independently with long-term externalizing outcomes, whereas IN symptoms were not. Between months 48 and 96, ADHD-HI/combined symptom subtype diagnoses predicted later oppositional defiant disorder diagnoses, oppositional defiant disorder diagnoses predicted later conduct disorder diagnoses, and conduct disorder diagnoses predicted later substance use disorder diagnoses. Evidence for environmental risk mediation (eg, parental monitoring, neighborhood violence) was also found.

conclusionFindings support trait impulsivity models of externalizing progression, whereby ADHD-HI/combined symptoms subtypes predispose to increasingly severe externalizing behaviors, which are magnified in contexts of environmental risk.

Indexed as

Attention Deficit and Disruptive Behavior DisordersImpulsive BehaviorAttention Deficit Disorder with HyperactivityChildFemaleHumansMaleProspective StudiesPsychiatric Status Rating ScalesADHDconduct disorderexternalizingimpulsivityinattention

Identifiers

PMID34098014
PMCPMC8642493
OpenAlexW3167010900

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.