Evidence map›Paper›PMID 34097952›Full record

ArticleToxicology in vitro : an international journal published in association with BIBRA2021

CD34+ derived macrophage and dendritic cells display differential responses to paraquat.

Leonie F H Fransen, Martin O Leonard

Abstract readComparative Study
In one paragraph

Article in Toxicology in vitro : an international journal published in association with BIBRA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Leonie F H FransenToxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, OX11 0RQ, UK. Electronic address: Leonie.Fransen@phe.gov.uk.
Martin O LeonardToxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, OX11 0RQ, UK. Electronic address: Martin.Leonard@phe.gov.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraquat (PQ) is a redox cycling herbicide known for its acute toxicity in humans. Airway parenchymal cells have been identified as primary sites for PQ accumulation, tissue inflammation and cellular injury. However, the role of immune cells in PQ induced tissue injury is largely unknown. To explore this further, primary cultures of human CD34+ stem cell derived macrophages (MC

Indexed as

AllergensAnimalsAntigens, CD34Cell SurvivalDendritic CellsHerbicidesHumansMacrophagesParaquatPyroglyphidaeAllergensAntigens, CD34HerbicidesParaquatLungMyeloidTempO-SeqTranscriptomics

Identifiers

PMID34097952
PMCPMC8444090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.