ArticleActa anaesthesiologica Scandinavica2021
Long-term consequences in critically ill COVID-19 patients: A prospective cohort study.
Article in Acta anaesthesiologica Scandinavica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 6 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Functional Recovery of Adults Following Acute COVID-19: A Systematic Review and Meta-Analysis.Physical therapy · 2025Pooled it
- Pooled it
- Pooled it
- ESCMID rapid guidelines for assessment and management of long COVID.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022Guideline
- Prevalence of post-acute COVID-19 syndrome symptoms at different follow-up periods: a systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022Pooled it
- Pooled it
- Factors affecting exercise performance at the 6-min walk test in long-COVID: a multicenter study from Italy.Internal and emergency medicine · 2026Article
- Corticosteroids and long-term pulmonary function after critical illness due to COVID-19- a single-center cohort study.BMC pulmonary medicine · 2025Observational
- Six-month trajectory of physical function in ICU survivors: Experience from an Eastern Cape centre.The South African journal of physiotherapy · 2025Article
- Evaluating Mental Health Outcomes in COVID-19 ICU Survivors: A Scoping Review of Measurement Tools.Journal of clinical medicine · 2024Article
- Prevalence of symptoms of anxiety and depression one year after intensive care unit admission for COVID-19.BMC psychiatry · 2024Article
- Review
- The long-term impact of COVID-19 pneumonia on pulmonary function and exercise capacity.Journal of thoracic disease · 2023Article
- Health related quality of life and its determinants in COVID-19 patients.Tuberkuloz ve toraks · 2023Article
- Article
- Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up.Intensive & critical care nursing · 2023Article
- Mid-Term Sequelae of Surviving Patients Hospitalized in Intensive Care Unit for COVID-19 Infection: The REHCOVER Study.Journal of clinical medicine · 2023Article
- Fluoxetine plus lithium for treatment of mental health impairment in Long Covid.Discover mental health · 2023Review
- Post-Intensive Care Syndrome Prevalence Six Months after Critical Covid-19: Comparison between First and Second Waves.Journal of rehabilitation medicine · 2022Article
- COVID-19 and Long-Term Outcomes: Lessons from Other Critical Care Illnesses and Potential Mechanisms.American journal of respiratory cell and molecular biology · 2022Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOVID-19 can cause severe disease with need of treatment in the intensive care unit (ICU) for several weeks. Increased knowledge is needed about the long-term consequences.
methodsThis is a single-center prospective follow-up study of COVID-19 patients admitted to the ICU for respiratory organ support between March and July 2020. Patients with invasive ventilation were compared with those with high-flow nasal oxygen (HFNO) or non-invasive ventilation (NIV) regarding functional outcome and health-related qualify of life. The mean follow-up time was 5 months after ICU discharge and included clinical history, three well-validated questionnaires about health-related quality of life and psychological health, pulmonary function test, 6-minute walk test (6MWT) and work ability. Data were analyzed with multivariable general linear and logistic regression models with 95% confidence intervals.
resultsAmong 248 ICU patients, 200 patients survived. Of these, 113 patients came for follow-up. Seventy patients (62%) had received invasive ventilation. Most patients reported impaired health-related quality of life. Approximately one-third suffered from post-traumatic stress, anxiety and depression. Twenty-six percent had reduced total lung capacity, 34% had reduced 6MWT and 50% worked fulltime. The outcomes were similar regardless of ventilatory support, but invasive ventilation was associated with more bodily pain (MSD -19, 95% CI: -32 to -5) and <80% total lung capacity (OR 4.1, 95% CI: 1.3-16.5).
conclusionAmong survivors of COVID-19 who required respiratory organ support, outcomes 5 months after discharge from ICU were largely similar among those requiring invasive compared to non-invasive ventilation.
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