Evidence map›Paper›PMID 34097752›Full record

ReviewPhotochemistry and photobiology2021

Antimicrobial Photodynamic Inactivation Using Topical and Superhydrophobic Sensitizer Techniques: A Perspective from Diffusion in Biofilms.

Caroline Coradi Tonon, Shoaib Ashraf, José Quílez Alburquerque, Alessandra Nara de Souza Rastelli, Tayyaba Hasan, Alan M Lyons, Alexander Greer

Abstract readReview
In one paragraph

Review in Photochemistry and photobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. AirborneAdvanced healthcare materials · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caroline Coradi TononWellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0058-9970
Shoaib AshrafWellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1218-4877
José Quílez AlburquerqueWellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1149-7433
Alessandra Nara de Souza RastelliWellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-6768-2670
Tayyaba HasanWellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0871-6057
Alan M LyonsDepartment of Chemistry, College of Staten Island, City University of New York, Staten Island, NY, USA.ORCID 0000-0003-4410-9756
Alexander GreerPh.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY, USA.ORCID 0000-0003-4444-9099

Funding

3D-Printed Superhydrophobic-Tipped Optical Fiber for Targeted Periodontal Photodynamic TherapyR44DE026083 · NIDCR · SINGLETO2 THERAPEUTICS, LLC · PI XU, QIANFENG · 2019 to 2020
$1.5M
NIDCR NIH HHS R44 DE026083
6 · The paper itself

Abstract

This review describes nanoparticle and dye diffusion in bacterial biofilms in the context of antimicrobial photodynamic inactivation (aPDI). aPDI requires the diffusion of a photosensitizer (Sens) into the biofilm and subsequent photoactivation of oxygen for the generation of reactive oxygen species (ROS) that inactivate microbes. Molecular diffusion in biofilms has been long investigated, whereas this review is intended to draw a logical link between diffusion in biofilms and ROS, a combination that leads to the current state of aPDI and superhydrophobic aPDI (SH-aPDI). This review should be of interest to photochemists, photobiologists and researchers in material and antimicrobial sciences as is ties together conventional aPDI with the emerging subject of SH-aPDI.

Indexed as

Anti-Infective AgentsPhotochemotherapyAnti-Bacterial AgentsBiofilmsHydrophobic and Hydrophilic InteractionsPhotosensitizing AgentsReactive Oxygen SpeciesAnti-Bacterial AgentsAnti-Infective AgentsPhotosensitizing AgentsReactive Oxygen Species

Identifiers

PMID34097752
PMCPMC10375486

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.