Evidence map›Paper›PMID 34097350›Full record

ArticleCancer science2021

Methyl CpG binding protein 2 promotes colorectal cancer metastasis by regulating N

Shuo Wang, Meifu Gan, Chaoyi Chen, Yi Zhang, Jianlu Kong, Honghe Zhang, Maode Lai

Abstract read
In one paragraph

Article in Cancer science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Review
  3. RNA mCell investigation · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. IGF2BPs as novel mGenes & diseases · 2024
    Review
  11. Review
  12. Review
  13. METTL14‑mediated RNA methylation in digestive system tumors.International journal of molecular medicine · 2023
    Review
  14. Review
  15. Review
  16. DNA 5mC and RNA mCell death and differentiation · 2023
    Article
  17. Article
  18. Emerging Regulatory Mechanisms of NPhenomics (Cham, Switzerland) · 2023
    Review
  19. The emerging role of mFrontiers in cell and developmental biology · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuo WangDepartment of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0000-0002-9027-9257
Meifu GanTaizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Linhai, China.
Chaoyi ChenDepartment of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.
Yi ZhangDepartment of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.
Jianlu KongDepartment of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.
Honghe ZhangDepartment of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.
Maode LaiDepartment of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.

Funding

Basic Public Welfare Research Project of Zhejiang Province LGF20H160023National Natural Science Foundation of China 91859204the 111 Project B13026
6 · The paper itself

Abstract

RNA N

Indexed as

Up-RegulationAdenosineAnimalsCell Line, TumorColorectal NeoplasmsDisease ProgressionGene Expression Regulation, NeoplasticHCT116 CellsHT29 CellsHumansKruppel-Like Factor 4Kruppel-Like Transcription FactorsMethyl-CpG-Binding Protein 2MethyltransferasesMiceNeoplasm TransplantationAdenosineKLF4 protein, humanKlf4 protein, mouseKruppel-Like Factor 4Kruppel-Like Transcription FactorsMECP2 protein, humanMethyl-CpG-Binding Protein 2MethyltransferasesMETTL14 protein, humanN-methyladenosinecolorectal cancerm6A methylationMeCP2metastasisMETTL14

Identifiers

PMID34097350
PMCPMC8353896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.