SynthesisSports medicine (Auckland, N.Z.)2021
Acute Effects of Training Loads on Muscle Damage Markers and Performance in Semi-elite and Elite Athletes: A Systematic Review and Meta-analysis.
Synthesis in Sports medicine (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Superset Versus Traditional Resistance Training Prescriptions: A Systematic Review and Meta-analysis Exploring Acute and Chronic Effects on Mechanical, Metabolic, and Perceptual Variables.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- The Effects of Pre-conditioning on Exercise-Induced Muscle Damage: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- The Acute Effect of Increasing Resistance Training Workload Volume on Muscle Damage Markers and Performance in Heavy Resistance-Trained Youth Athletes.Sports (Basel, Switzerland) · 2026Article
- Health-related effects of walking football in older adults: A real-world longitudinal study across a season comparing two age groups.PloS one · 2026Article
- Acute and Chronic Effects of a High-Intensity Interval Training Shock Microcycle on Cell-Free DNA: A Randomized Controlled Trial.Sports medicine - open · 2025Article
- The 4Rs Framework of Sports Nutrition: An Update with Recommendations to Evaluate Allostatic Load in Athletes.Life (Basel, Switzerland) · 2025Review
- The effect of eccentric arm cycling on muscle damage and injury-related biomarkers.Clinical physiology and functional imaging · 2025Article
- Inflammation and cognitive performance in elite athletes: A cross-sectional study.Brain, behavior, & immunity - health · 2024Article
- Acute Response to Training after Returning from the Off-Season in Elite Rugby League Athletes.Journal of human kinetics · 2024Article
- Disentangling the dynamic interplay between muscle damage and energetics in male boxers during a short training block.Biology of sport · 2024Article
- Association between Gray-Scale Ultrasound Imaging and Serological Creatine Kinase for Quantifying Exercise-Induced Muscle Damage: An Observational Study.Bioengineering (Basel, Switzerland) · 2023Article
- Intravenous Injection of Sodium Hyaluronate Diminishes Basal Inflammatory Gene Expression in Equine Skeletal Muscle.Animals : an open access journal from MDPI · 2023Article
- A Carnitine-Containing Product Improves Aspects of Post-Exercise Recovery in Adult Horses.Animals : an open access journal from MDPI · 2023Article
- Exercise-Induced Muscle Damage and Protein Intake: A Bibliometric and Visual Analysis.Nutrients · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between exercise-induced muscle damage (EIMD) indicators and acute training loads (TL) is yet to be reviewed extensively in semi-elite and elite athlete populations.
objectivesThe objectives of this systematic review and meta-analysis were threefold: (1) to evaluate studies of EIMD following the initial period of the preseason in semi-elite and elite athletes: (2) to examine acute physiological and performance responses across two periods of the season with similar TL; and (3) to examine acute physiological and performance responses to acute changes in TL during the season.
methodsThe CINAHL, PubMed, Scopus, SPORTDiscus and Web of Science databases were systematically searched for studies that investigated: (1) semi-elite or elite athletes in team or individual sports following a periodised training programme; and (2) measured acute responses to training. Studies were excluded if: (1) conducted in animals; (2) non-English language; or (3) a conference abstract, review or case report. The Kmet Quality Scoring of Quantitative Studies tool was used for study appraisal. SYNTHESIS
methodsData were quantitatively analysed by generating forest plots to report test statistics for statistical significance and inter-trial heterogeneity.
resultsOf the included studies (n = 32), athletes experienced greater creatine kinase (CK) concentrations (Z = 4.99, p < 0.00001, I LIMITATIONS: This review included varying age, sex, sports and competition levels. The group level meta-analysis failed to identify within-athlete or position-specific differences across time.
conclusionBlood biomarkers of EIMD may not differ across periods of similar TL, however can be considered a sensitive monitoring tool for assessing responses following acute TL changes in semi-elite and elite athletes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.