Evidence map›Paper›PMID 34097265›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Analyses of Epigenetic Modification in Environmental Pollutants-Induced Neurotoxicity.

Guangxia Yu, Zhenkun Guo, Huangyuan Li

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Epigenetics in neurodegenerative disorders induced by pesticides.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Guangxia Yu *The Key Laboratory of Environment and Health, School of Public Health, Fujian Medical University, Fuzhou, China.
Zhenkun Guo *The Key Laboratory of Environment and Health, School of Public Health, Fujian Medical University, Fuzhou, China.
Huangyuan LiThe Key Laboratory of Environment and Health, School of Public Health, Fujian Medical University, Fuzhou, China. fmulhy@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetics is one of the most rapidly expanding fields in biology, which plays important roles in environmental pollutant-induced neurotoxicity. Analyses of epigenetic modification is of great significance in providing more accurate information for the risk assessment and management of harmful factors. However, few studies have systematically summarized the analysis and detection methods for epigenetic modification. In this chapter, we summarized several popular methods for analyses of epigenetic modifications, including Methylated DNA Immunoprecipitation Sequencing (MeDIP-Seq) for genome-wide DNA methylation analyses, Quantitative Methylation Specific PCR (qMSP) for genome-specific DNA methylation analyses, methylated RNA immunoprecipitation sequencing (MeRIP-seq) for genome-wide RNA methylation analyses, MeRIP-qPCR for genome-specific RNA methylation analyses, qRT-PCR for the non-coding RNA, and western blot for the histone modification analyses. It could be helpful to the research about environmental epigenetic toxicology.

Indexed as

AnimalsDNADNA MethylationEnvironmental PollutantsEpigenesis, GeneticEpigenomicsHistone CodeHumansImmunoprecipitationPolymerase Chain ReactionRNASequence Analysis, DNASequence Analysis, RNADNAEnvironmental PollutantsRNAChromatin structureDNA methylationEpigeneticsHistone modificationsNeurotoxicologyNon-coding RNARNA methylation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.