Evidence map›Paper›PMID 34097226›Full record

ArticleInternational journal of computer assisted radiology and surgery2021

Liver disease classification from ultrasound using multi-scale CNN.

Hui Che, Lloyd G Brown, David J Foran, John L Nosher, Ilker Hacihaliloglu

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Article in International journal of computer assisted radiology and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Hui CheDepartment of Biomedical Engineering, Rutgers University, Piscataway, NJ, USA.
Lloyd G BrownDepartment of Surgery, Rutgers New Jersey Medical School, New Brunswick, NJ, USA.
David J ForanRutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
John L NosherDepartment of Radiology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Ilker HacihalilogluDepartment of Biomedical Engineering, Rutgers University, Piscataway, NJ, USA. ilker.hac@soe.rutgers.edu.ORCID http://orcid.org/0000-0003-3232-8193
Rutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUltrasound (US) is the preferred modality for fatty liver disease diagnosis due to its noninvasive, real-time, and cost-effective imaging capabilities. However, traditional B-mode US is qualitative, and therefore, the assessment is very subjective. Computer-aided diagnostic tools can improve the specificity and sensitivity of US and help clinicians to perform uniform diagnoses.

methodsIn this work, we propose a novel deep learning model for nonalcoholic fatty liver disease classification from US data. We design a multi-feature guided multi-scale residual convolutional neural network (CNN) architecture to capture features of different receptive fields. B-mode US images are combined with their corresponding local phase filtered images and radial symmetry transformed images as multi-feature inputs for the network. Various fusion strategies are studied to improve prediction accuracy. We evaluate the designed network architectures on B-mode in vivo liver US images collected from 55 subjects. We also provide quantitative results by comparing our proposed multi-feature CNN architecture against traditional CNN designs and machine learning methods.

resultsQuantitative results show an average classification accuracy above 90% over tenfold cross-validation. Our proposed method achieves a 97.8% area under the ROC curve (AUC) for the patient-specific leave-one-out cross-validation (LOOCV) evaluation. Comprehensive validation results further demonstrate that our proposed approaches achieve significant improvements compared to training mono-feature CNN architectures ([Formula: see text]).

conclusionsFeature combination is valuable for the traditional classification methods, and the use of multi-scale CNN can improve liver classification accuracy. Based on the promising performance, the proposed method has the potential in practical applications to help radiologists diagnose nonalcoholic fatty liver disease.

Indexed as

Liver DiseasesNeural Networks, ComputerHumansMachine LearningUltrasonographyClassificationDeep learningNonalcoholic fatty liver diseaseUltrasound

Identifiers

PMID34097226
OpenAlexW3170210531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.