Evidence map›Paper›PMID 34097099›Full record

ArticleExperimental brain research2021

Behavioural tagging: Effect of novelty exploration on plasticity related molecular signatures.

Mehar Naseem, Shruti Vishnoi, Medha Kaushik, Suhel Parvez

Abstract read
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In one paragraph

Article in Experimental brain research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mehar NaseemDepartment of Toxicology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, 110062, India.
Shruti VishnoiDepartment of Toxicology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, 110062, India.
Medha KaushikDepartment of Toxicology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, 110062, India.
Suhel ParvezDepartment of Toxicology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, 110062, India. drsuhelparvez@yahoo.com.ORCID http://orcid.org/0000-0002-6318-6506
Jamia Hamdard · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Learning and memory are one of those frontier areas of neurobiology which attract us to investigate the intricacy of this process. Here, we aimed to investigate the general mechanism of "Behavioural Tagging and Capture" in long term memory (LTM) formation and to find the key factors playing role in consolidation of LTM. In this study, we've shown that not only plasticity related proteins (PRPs) but neurotransmitters and immediate early genes (IEGs) also play an important role in memory formation process. It's very well evident that memory traces can last longer if close in time novelty is introduced around memory encoding. Here our results point out that this novelty exploration acts as a modulator in memory consolidation by providing PRPs such as brain-derived neurotrophic factor (BDNF), cAMP response element-binding protein (CREB), enhancing neurotransmitters (Dopamine), IEGs (cFos) and some enzymes such as acetylcholinesterase (AChE), monoamine oxidase (MAO), sodium-potassium ATPase (Na

Indexed as

Memory ConsolidationRecognition, PsychologyAnimalsHippocampusMemoryMemory, Long-TermRatsRats, WistarAnisomycinBehavioural taggingLong term memoryPlasticity related proteinsPrefrontal cortex

Identifiers

PMID34097099
OpenAlexW3170405197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.