ReviewDer Nervenarzt2021
[Disease burden of borderline personality disorder: cost of illness, somatic comorbidity and mortality].
Review in Der Nervenarzt, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- The Association Between Emotional Intelligence and Borderline Personality Disorder: A Meta-Analysis.International journal of psychology : Journal international de psychologie · 2025Pooled it
- Pooled it
- Pharmacological interventions for people with borderline personality disorder.The Cochrane database of systematic reviews · 2022Pooled it
- [Experienced stigmatization within the somatic healthcare system : A survey of people with diagnoses of severe mental illnesses].Der Nervenarzt · 2026Article
- Medication Use and Quality of Life in Older Adults with Personality Disorders.Drugs & aging · 2025Observational
- Sleep disturbance and maladaptive sleep-related cognitions in borderline personality disorder in the longitudinal McLean Study of Adult Development.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- [Physical health in people with severe mental illness].Der Nervenarzt · 2025Review
- Comparison of 8-vs-12 weeks, adapted dialectical behavioral therapy (DBT) for borderline personality disorder in routine psychiatric inpatient treatment-A naturalistic study.Scientific reports · 2024Article
- Evidence of deviant parasympathetic response to social exclusion in women with borderline personality disorder.European archives of psychiatry and clinical neuroscience · 2024Article
- Differences in diagnostic rules used to determine borderline personality disorder impact prevalence and associations with clinically relevant variables: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions-III.Personality disorders · 2024Article
- Beyond clinical observations: a scoping review of AI-detectable observable cues in borderline personality disorder.Frontiers in psychiatry · 2024Article
- Mother-child interactions in adolescents with borderline personality disorder traits and the impact of early life maltreatment.Child and adolescent psychiatry and mental health · 2023Article
- Case report: Brief, intensive EMDR therapy for borderline personality disorder: results of two case studies with one year follow-up.Frontiers in psychiatry · 2023Article
- Interventions to Promote the Utilization of Physical Health Care for People with Severe Mental Illness: A Scoping Review.International journal of environmental research and public health · 2022Article
- Patients With Personality Disorders in Everyday Clinical Practice–Implications of the ICD-11.Deutsches Arzteblatt international · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere mental illnesses (SMI) are characterized by high psychosocial impairment as well as by increased somatic morbidity and mortality. The term SMI commonly includes psychotic, bipolar and severe unipolar depressive disorders but borderline personality disorder (BPD) also shows severe sequelae of the disease. MATERIAL AND
methodsPublished reviews and studies since 2010 examining disease burden of BPD, in terms of direct and indirect costs of illness, somatic comorbidity, and mortality were included. Furthermore, administrative data (clinically recorded billing data in Germany), comorbidity and mortality from a comprehensive analysis (n > 59 million, age ≥ 18 years) are reported.
resultsInternational studies reveal an increased disease burden, comorbidity, and mortality for BPD. In Germany BPD (administrative 1‑year prevalence 0.34%) is associated with increased rates of somatic sequelae of trauma, hepatitis, HIV, COPD, asthma, and obesity. The estimated reduced life expectancy is 5.0-9.3 years of life lost (depending on age and sex). DISCUSSION: The burden of disease in BPD is clearly increased (cost of illness, somatic comorbidity and mortality). The increased mortality can mainly be explained by deaths as a consequence of poor physical health and associated BPD-related health behavior and only to a lesser degree by suicide. These results highlight the importance of classifying BPD as an SMI and the necessity to provide not only psychotherapeutic and psychiatric but also adequate somatic prevention and treatment. Individual improvement of everyday care as well as establishing new interdisciplinary and multiprofessional services could enhance health equality for people with BPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.