Evidence map›Paper›PMID 34096867›Full record

ArticleeLife2021

Functional biology in its natural context: A search for emergent simplicity.

Joy Bergelson, Martin Kreitman, Dmitri A Petrov, Alvaro Sanchez, Mikhail Tikhonov

Abstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Evolutionary repeatability of emergent properties of ecological communities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Testing hypotheses of a coevolutionary key innovation reveals a complex suite of traits involved in defusing the mustard oil bomb.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joy Bergelson *Department of Ecology & Evolution, University of Chicago, Chicago, United States.ORCID 0000-0001-7893-7387
Martin Kreitman *Department of Ecology & Evolution, University of Chicago, Chicago, United States.
Dmitri A Petrov *Department of Biology, Stanford University, Stanford, United States.ORCID 0000-0002-3664-9130
Alvaro Sanchez *Department of Ecology & Evolutionary Biology, Yale University, New Haven, United States.ORCID 0000-0002-2292-5608
Mikhail Tikhonov *Department of Physics, Washington University in St Louis, St. Louis, United States.ORCID 0000-0002-9558-1121

Funding

Genomics of rapid adaptation in the lab and in the wildR35GM118165 · NIGMS · STANFORD UNIVERSITY · PI Dmitri Petrov · 2016 to 2026
$8.3M
NIGMS NIH HHS R35 GM118165
6 · The paper itself

Abstract

The immeasurable complexity at every level of biological organization creates a daunting task for understanding biological function. Here, we highlight the risks of stripping it away at the outset and discuss a possible path toward arriving at emergent simplicity of understanding while still embracing the ever-changing complexity of biotic interactions that we see in nature.

Indexed as

Biological EvolutionModels, BiologicalSystems BiologyAnimalsBiotaHigh-Throughput Screening AssaysHumanseco-evolutionary dynamicsecological contextevolutionary biologyfunctional biologyphysics of living systemssystems biology

Identifiers

PMID34096867
PMCPMC8184206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.