Evidence map›Paper›PMID 34096777›Full record

ArticleJournal of bacteriology2021

Cautionary Notes on the Use of Arabinose- and Rhamnose-Inducible Expression Vectors in Pseudomonas aeruginosa.

Emily A Williams McMackin, Jodi M Corley, Sardar Karash, Jeremiah Marden, Matthew C Wolfgang, Timothy L Yahr

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  13. Expansion of healthcare-associated hypervirulent KPC-2-producingOne health (Amsterdam, Netherlands) · 2023
    Article
  14. Article
  15. Cell arrangement impacts metabolic activity and antibiotic tolerance inbioRxiv : the preprint server for biology · 2023
    Article
  16. TheInternational journal of molecular sciences · 2023
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Emily A Williams McMackinDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Jodi M CorleyDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Sardar KarashDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Jeremiah MardenDepartment of Microbiology & Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Matthew C WolfgangDepartment of Microbiology & Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Timothy L YahrDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
University of Iowa · USUniversity of North Carolina at Chapel Hill · US

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Amy Leanne Ryan · 1998 to 2026
$30.5M
TRAINING IN MECHANISMS OF PARASITISMT32AI007511 · NIAID · UNIVERSITY OF IOWA · PI BUTLER, NOAH SULLIVAN, WEBER, MARY · 1996 to 2025
$8.1M
Regulation of Pseudomonas aeruginosa type III secretionR01AI055042 · NIAID · UNIVERSITY OF IOWA · PI YAHR, TIMOTHY L · 2003 to 2021
$4.4M
NIAID NIH HHS R01 AI055042NIAID NIH HHS T32 AI007511NIDDK NIH HHS P30 DK054759
6 · The paper itself

Abstract

The Pseudomonas aeruginosa virulence factor regulator (Vfr) is a cyclic AMP (cAMP)-responsive transcription factor homologous to the Escherichia coli cAMP receptor protein (CRP). Unlike CRP, which plays a central role in E. coli energy metabolism and catabolite repression, Vfr is primarily involved in the control of P. aeruginosa virulence factor expression. Expression of the Vfr regulon is controlled at the level of

Indexed as

Gene Expression Regulation, BacterialArabinoseBacterial ProteinsCatabolite RepressionCyclic AMP Receptor ProteinGenetic VectorsPromoter Regions, GeneticPseudomonas aeruginosaRegulonRhamnoseTranscription FactorsVirulence FactorsArabinoseBacterial ProteinsCyclic AMP Receptor ProteinRhamnoseTranscription FactorsVfr protein, Pseudomonas aeruginosaVirulence Factorsarabinosecyclic AMPPseudomonas aeruginosarhamnoseVfr

Identifiers

PMID34096777
PMCPMC8297530
OpenAlexW3171122375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.