Evidence map›Paper›PMID 34096337›Full record

ArticleJournal of the American Heart Association2021

Outcomes of Rescue Endovascular Treatment of Emergent Large Vessel Occlusion in Patients With Underlying Intracranial Atherosclerosis: Insights From STAR.

Sami Al Kasab, Eyad Almallouhi, Ali Alawieh, Stacey Wolfe, Kyle M Fargen, Adam S Arthur, Nitin Goyal, Travis Dumont, Peter Kan, Joon-Tae Kim and 11 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 66 citations in OpenAlex.

  1. Trial
  2. Trial
  3. RESCUE-ICAS: Rationale and Study Design.Stroke (Hoboken, N.J.) · 2023
    Trial
  4. Article
  5. Article
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  8. Management of intracranial arterial stenosis during mechanical thrombectomy: Survey of neuro-interventionalists.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  9. Review
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  11. Comparative analysis of outcome-associated factors following endovascular treatment for intracranial atherosclerotic disease and cardioembolism: A subanalysis of the K-NET registry.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  12. Article
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  14. Determinants of day-1 stent patency following rescue intracranial stenting in failed intracranial thrombectomy.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 19 institutions in 7 countries.

Sami Al KasabDepartment of Neurology Medical University of South Carolina Charleston SC.
Eyad AlmallouhiDepartment of Neurology Medical University of South Carolina Charleston SC.
Ali AlawiehDepartment of Neurosurgery Emory University School of Medicine Atlanta GA.
Stacey WolfeDepartment of Neurosurgery Wake Forest School of Medicine Winston Salem NC.
Kyle M FargenDepartment of Neurosurgery Wake Forest School of Medicine Winston Salem NC.
Adam S ArthurDepartment of Neurosurgery Semmes-Murphey Neurologic and Spine Clinic University of Tennessee Health Science Center Memphis TN.
Nitin GoyalDepartment of Neurosurgery Semmes-Murphey Neurologic and Spine Clinic University of Tennessee Health Science Center Memphis TN.
Travis DumontDepartment of Neurosurgery University of Arizona Health Sciences Tucson AZ.
Peter KanDepartment of Neurosurgery Baylor School of Medicine Houston TX.
Joon-Tae KimDepartment of Neurology Chonnam National University Hospital Seoul South Korea.
Reade De LeacyDepartment of Neurosurgery Mount Sinai Health System New York NY.
Ilko MaierDepartment of Neurology University Medical Center Göttingen Göttingen Germany.
Joshua OsbunDepartment of Neurosurgery Washington University of School of Medicine St. Louis MO.
Ansaar RaiDepartment of Radiology West Virginia School of Medicine Morgantown WV.
Pascal JabbourDepartment of Neurosurgery Thomas Jefferson University Hospitals Philadelphia PA.
Jonathan A GrossbergDepartment of Neurosurgery Emory University School of Medicine Atlanta GA.
Min S ParkDepartment of Neurosurgery University of Virginia Charlottesville VA.
Robert M StarkeDepartment of Neurosurgery University of Miami Health System Miami FL.
Roberto CrosaDepartment of Neurosurgery Endovascular Neurological Center Médica Uruguaya Montevideo Uruguay.
Alejandro M SpiottaDepartment of Neurosurgery Medical University of South Carolina Charleston SC.
STAR collaborators †
Medical University of South Carolina · USEmory University · USUniversity of Tennessee Health Science Center · USWake Forest University · USAlexion Pharma (Switzerland) · CHBaylor School · USChonnam National University Hospital · KRDr. Jose N. Rodriguez Memorial Hospital · PHLucas Research · USMount Sinai Health System · USNickel Institute · CAPeterson (Norway) · NOThomas Jefferson University Hospital · USUniversitätsmedizin Göttingen · DEUniversity of Arizona · USUniversity of Miami Health System · USUniversity of Virginia · USWalker (United States) · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Some emergent large vessel occlusions (ELVOs) are refractory to reperfusion because of underlying intracranial atherosclerosis (ICAS), often requiring rescue therapy (RT) with balloon angioplasty, stenting, or both. In this study, we investigate the safety, efficacy, and long-term outcomes of RT in the setting of mechanical thrombectomy for ICAS-related ELVO. Methods and Results We queried the databases of 10 thrombectomy-capable centers in North America and Europe included in STAR (Stroke Thrombectomy and Aneurysm Registry). Patients with ELVO who underwent ICAS-related RT were included. A matched sample was produced for variables of age, admission National Institute of Health Stroke Scale, Alberta Stroke Program Early CT Score, onset to groin puncture time, occlusion site, and final recanalization. Out of 3025 patients with MT, 182 (6%) patients required RT because of underlying ICAS. Balloon angioplasty was performed on 122 patients, and 117 patients had intracranial stenting. In the matched analysis, 141 patients who received RT matched to a similar number of controls. The number of thrombectomy passes was higher (3 versus 1,

Indexed as

Angioplasty, BalloonThrombectomyAgedAged, 80 and overDatabases, FactualEuropeFemaleFunctional StatusHumansIntracranial ArteriosclerosisIschemic StrokeMaleMiddle AgedNorth AmericaRecovery of FunctionRegistriesacute strokeballoon angioplastyintracranial atherosclerosismechanical thrombectomyrescue therapystenting

Identifiers

PMID34096337
PMCPMC8477850
OpenAlexW3170475577

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.