Evidence map›Paper›PMID 34096335›Full record

ArticleJournal of the American Heart Association2021

Left Atrial Appendage Morphology and Local Thrombogenesis-Related Blood Parameters in Patients With Atrial Fibrillation.

Buyun Xu, Ye Du, Chao Xu, Yong Sun, Fang Peng, Shengkai Wang, Jie Pan, Yuanqing Lou, Yangbo Xing

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Buyun XuDepartment of Cardiology Shaoxing People's Hospital, Shaoxing Hospital, Zhejiang University School of Medicine Zhejiang P. R. China.
Ye DuDepartment of Neurology Shaoxing People's Hospital, Shaoxing Hospital, Zhejiang University School of Medicine Zhejiang P. R. China.
Chao XuDepartment of Cardiology Shaoxing People's Hospital, Shaoxing Hospital, Zhejiang University School of Medicine Zhejiang P. R. China.
Yong SunDepartment of Cardiology Shaoxing People's Hospital, Shaoxing Hospital, Zhejiang University School of Medicine Zhejiang P. R. China.
Fang PengDepartment of Cardiology Shaoxing People's Hospital, Shaoxing Hospital, Zhejiang University School of Medicine Zhejiang P. R. China.
Shengkai WangDepartment of Cardiology Shaoxing People's Hospital, Shaoxing Hospital, Zhejiang University School of Medicine Zhejiang P. R. China.
Jie PanDepartment of Cardiology The First Affiliated Hospital of Shaoxing University Zhejiang P. R. China.
Yuanqing LouDepartment of Cardiology The First Affiliated Hospital of Shaoxing University Zhejiang P. R. China.
Yangbo XingDepartment of Cardiology Shaoxing People's Hospital, Shaoxing Hospital, Zhejiang University School of Medicine Zhejiang P. R. China.
Shaoxing People's Hospital · CNShaoxing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Left atrial appendage (LAA) morphology predicts stroke risk in patients with atrial fibrillation. However, it is not precisely understood how LAA morphology influences stroke risk. The present study aimed to investigate the relationship between LAA morphology and local thrombogenesis-related blood parameters in LAA. Methods and Results We enrolled 205 patients undergoing catheter ablation of atrial fibrillation. The prevalence of chicken wing-, cactus-, windsock-, and cauliflower-type LAAs were 23.9%, 32.7%, 29.3%, and 14.1%, respectively. Blood samples were collected from the femoral vein, left atrium, and LAA in each patient. The levels of blood parameters were tested for each blood sample. The cauliflower-type LAA was associated with elevated platelet P-selectin expression, and interleukin-6 levels and with lower NO levels in LAA blood samples (

Indexed as

HemostasisMultidetector Computed TomographyAgedAtrial AppendageAtrial FibrillationBiomarkersBlood PlateletsCatheter AblationEndothelial CellsFemaleHumansInflammation MediatorsInterleukin-6MaleMiddle AgedNitric OxideBiomarkersIL6 protein, humanInflammation MediatorsInterleukin-6Nitric OxidePlasminogen Activator Inhibitor 1P-SelectinSELP protein, humanSERPINE1 protein, humanvon Willebrand Factoratrial fibrillationcoagulationendothelial dysfunctioninflammationleft atrial appendage

Identifiers

PMID34096335
PMCPMC8477894
OpenAlexW3170514045

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.