Evidence map›Paper›PMID 34096317›Full record

Observational studyJournal of the American Heart Association2021

Chronic Cardio-Metabolic Disease Increases the Risk of Worse Outcomes Among Hospitalized Patients With COVID-19: A Multicenter, Retrospective, and Real-World Study.

Qijian Chen, Lingling Wang, Chang Li, Weihua Hu, Yameng Fan, Zaishu Chen, Longlong Wu, Zhanjin Lu, Jianfang Ye, Shiyan Chen and 4 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. COVID-19 in Kidney Transplant Recipients With Diabetes Mellitus: A Propensity Score Matching Analysis.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Qijian ChenDepartment of Emergency the Fifth Hospital in Wuhan Wuhan Hubei China.
Lingling WangDepartment of Endocrinology & Metabolism the Fifth Affiliated Hospital of Sun Yat-sen University Zhuhai Guangdong China.
Chang LiDepartment of Cardiology Hubei No. 3 People's Hospital of Jianghan University Wuhan Hubei China.
Weihua HuDepartment of Respiratory Medicine the First Hospital of Jingzhou Clinical Medical College Yangtze University Jingzhou Hubei China.
Yameng FanSchool of Health Sciences Wuhan University Wuhan Hubei China.
Zaishu ChenPeople's Hospital of Jiayu County Xianning Hubei China.
Longlong WuPeople's Hospital of Nanzhang County Nanzhang Hubei China.
Zhanjin LuDepartment of Endocrinology & Metabolism the Fifth Affiliated Hospital of Sun Yat-sen University Zhuhai Guangdong China.
Jianfang YeDepartment of Endocrinology & Metabolism the Fifth Affiliated Hospital of Sun Yat-sen University Zhuhai Guangdong China.
Shiyan ChenDepartment of Endocrinology & Metabolism the Fifth Affiliated Hospital of Sun Yat-sen University Zhuhai Guangdong China.
Junlu TongDepartment of Endocrinology & Metabolism the Fifth Affiliated Hospital of Sun Yat-sen University Zhuhai Guangdong China.
Liemin RuanCentral Laboratory Ningbo First Hospital of Zhejiang University Ningbo Zhejiang China.
Jin MeiCentral Laboratory Ningbo First Hospital of Zhejiang University Ningbo Zhejiang China.
Hongyun LuDepartment of Endocrinology & Metabolism Zhuhai Hospital Affiliated with Jinan UniversityZhuhai People's Hospital Zhuhai Guangdong China.
Sun Yat-sen University · CNWuhan University · CNJianghan University · CNJinan University · CNNanzhong Zhangzhongjing Hospital · CNNingbo First Hospital · CNWenzhou University · CNXianning Central Hospital · CNYangtze University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Although chronic cardio-metabolic disease is a common comorbidity among patients with COVID-19, its effects on the clinical characteristics and outcome are not well known. Methods and Results This study aimed to explore the association between underlying cardio-metabolic disease and mortality with COVID-19 among hospitalized patients. This multicenter, retrospective, and real-world study was conducted from January 22, 2020 to March 25, 2020 in China. Data between patients with and without 5 main cardio-metabolic diseases including hypertension, diabetes mellitus, coronary heart disease, cerebrovascular disease, and hyperlipidemia were compared. A total of 1303 hospitalized patients were included in the final analysis. Of them, 520 patients (39.9%) had cardio-metabolic disease. Compared with patients without cardio-metabolic disease, more patients with cardio-metabolic disease had COVID-related complications including acute respiratory distress syndrome (9.81% versus 3.32%;

Indexed as

HospitalizationAdultAgedChinaChronic DiseaseComorbidityCOVID-19Disease ProgressionFemaleHospital MortalityHumansIncidenceMaleMetabolic SyndromeMiddle AgedPrognosiscardio‐metabolic diseasecomplicationsCOVID‐19in‐hospital mortalityrisk factorsSARS‐CoV‐2

Identifiers

PMID34096317
PMCPMC8477891
OpenAlexW3168914200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.